NeuroPsy InfoHub — informație de încredere despre neurodiversitate

StudiuAdicțiiÎncredere bună19.06.2026

Machine Learning Models for Differentiating Alcohol and Substance Use Disorders Using Hemogram Parameters

A retrospective study explored whether routine blood count parameters analyzed with machine learning could help distinguish between alcohol use disorder, substance use disorder, and healthy controls in 228 participants. Random Forest models achieved 81.6% accuracy in classification, identifying monocyte count, basophil count, and RDW-CV as significant differentiating parameters, though sensitivity varied across disorder types.

StudiuAdicțiiÎncredere înaltă19.06.2026

Glucocorticoid receptor blockade reverses heroin and alcohol withdrawal-induced hyperalgesia in rats

This preclinical study demonstrates that mifepristone, a glucocorticoid receptor antagonist, can reverse pain hypersensitivity (hyperalgesia) occurring during alcohol and opioid withdrawal in rats, with differential effects depending on substance and sex. The findings suggest targeting glucocorticoid signaling may address withdrawal-related pain, a significant barrier to addiction recovery.

StudiuAdicțiiÎncredere bună19.06.2026

Development of the Inclusion of Videogame in the Self (IVS) Scale: A Symbol-Based Screening Tool for Internet Gaming Disorder in Youth

This study developed and evaluated the IVS scale, a brief pictorial screening instrument for Internet Gaming Disorder in children and adolescents, finding that a single-item measure of the perceived relationship with a favorite game showed strong sensitivity (100%) as a quick screening proxy. While the tool shows promise for identifying at-risk youth, the high false-positive rate (45%) and limited full-scale diagnostic accuracy indicate the need for further validation in larger, more diverse populations.

StudiuAdicțiiÎncredere bună19.06.2026

Should Gaming Disorder Diagnostic Criteria Include Non-Digital Gaming Activities?

This academic commentary argues that ICD-11's gaming disorder definition focuses exclusively on digital gaming and may overlook potential harms from non-digital gaming activities like collectible card games and tabletop games, which share similar monetization mechanisms with online games. The authors call for empirical research to examine whether non-digital gaming produces similar addiction patterns and harms as digital gaming, and whether such research might inform prevention strategies.

StudiuAdicțiiÎncredere bună19.06.2026

Psychological Mechanisms in Video Game Monetization: A Typology of Contemporary Strategies Beyond Loot Boxes

This research synthesizes literature on video game monetization systems to identify how design strategies exploit psychological mechanisms—including reinforcement, fear of missing out, and loss aversion—across different payment models. The study categorizes monetization into four types and discusses their association with problematic gaming and behavioral addiction, proposing frameworks for consumer protection.

StudiuAdicțiiÎncredere înaltă19.06.2026

Geographic Availability of Medications for Alcohol Use Disorder in US Treatment Facilities (2017-2023)

This nationwide study tracked trends in availability of evidence-based medications (acamprosate, disulfiram, naltrexone) for alcohol use disorder across US substance use disorder treatment facilities from 2017 to 2023. The research identified geographic disparities and county-level characteristics associated with access to these medications to inform expansion of treatment capacity.

StudiuAdicțiiÎncredere bună19.06.2026

Behavioral addictions in Africa: Emerging trends, challenges, and policy implications

Behavioral addictions such as problematic internet use, gaming, and gambling are rising public health concerns in Africa due to digitalization and socioeconomic changes, with significant impact on youth. The continent faces substantial obstacles including insufficient epidemiological data, culturally inappropriate assessment tools, and weak mental health infrastructure, necessitating culturally adapted research and evidence-based policy responses.

StudiuAdicțiiÎncredere bună19.06.2026

Implementation outcomes of video-observed oral fluid self-collection for drug testing in substance use disorder treatment: a pilot study

This pilot study evaluated the acceptability, feasibility, and usability of video-observed oral fluid self-collection for remote drug screen monitoring in substance use disorder treatment across outpatient and residential settings. Results showed the approach was generally acceptable, appropriate, and feasible (scores exceeding 3.0 threshold), though system usability scores were below average and variable, suggesting potential for refinement in real-world implementation.

StudiuAdicțiiÎncredere înaltă19.06.2026

Deep Learning Model for Predicting Alcohol Use Disorder Risk in Adolescents and Young Adults

Researchers developed a deep learning model using longitudinal data to predict individualized risk of developing alcohol use disorder in adolescents and young adults who drink, identifying biological sex, delinquency, and personality traits as key risk factors. The model demonstrated good predictive performance (AUC 0.86 at 1-6 year follow-up) with appropriate validation and calibration metrics.

StudiuAdicțiiÎncredere bună19.06.2026

Metacognitions, Emotion Regulation, and Gambling Disorder: A Two-Wave Longitudinal Study

This longitudinal study examined how metacognitions about gambling and emotion regulation jointly contribute to gambling disorder among 585 Chinese adults using cross-lagged panel analysis. Results showed that both positive and negative metacognitions about gambling were stronger predictors of gambling disorder than emotion regulation alone, and identified a bidirectional relationship suggesting a vicious cycle between metacognitions and gambling disorder that emotion regulation may help interrupt.

StudiuAdicțiiÎncredere înaltă19.06.2026

Gamer Identity and Addiction-Related Nostalgia as Barriers to Gaming Disorder Recovery

This study of 877 individuals in recovery from gaming disorder found that continued identification as a gamer strengthens nostalgic longing for gaming's perceived psychological benefits, which undermines recovery through increased loneliness, depression, and anxiety. Abstinent individuals showed better recovery motivation than those attempting reduced gaming, suggesting that complete disidentification from the gamer role may facilitate sustained recovery.

StudiuAdicțiiÎncredere înaltă19.06.2026

Behavioral Addictions in Latin American Adolescents: Prevalence, Mental Health Comorbidities, and Care Gaps

This narrative review synthesizes evidence on behavioral addictions (internet addiction, gaming disorder, problematic smartphone/social media use) in Latin American adolescents aged 10-19, finding prevalence estimates ranging from 10.6% to 54.9% with significant associations to ADHD, depression, anxiety, and suicidality. The review identifies critical gaps including lack of validated regional instruments, limited evidence-based interventions, and insufficient specialist workforce capacity in the region.

StudiuAdicțiiÎncredere bună19.06.2026

Off-label and investigational drugs in the treatment of gambling disorder: a critical review

This review examines various pharmacological agents investigated for treating gambling disorder, including SSRIs, opioid antagonists, anticonvulsants, and other drugs, finding promising results particularly with opioid antagonists. The authors note significant limitations including small sample sizes, inconsistent study designs, and contradictory findings that restrict clinical applicability of current evidence.

StudiuAdicțiiÎncredere bună19.06.2026

Implicit Associations and Approach-Avoidance Tendencies in Problematic Social Network Use and Tobacco Use Disorder: A Laboratory Comparison Study

This laboratory study compared implicit cognitive processes (associations and approach-avoidance tendencies) across 178 participants with problematic social network use, risky use, non-problematic use, and tobacco use disorder using validated psychological tests. While initial results showed differences in implicit associations between groups, effects diminished when controlling for age and comorbid psychiatric symptoms, suggesting overlapping but distinct mechanisms between behavioral and substance addictions.

StudiuAdicțiiÎncredere bună19.06.2026

Progressive Aerobic Training Reduces Internet Gaming Disorder Severity and Alters Default Mode Network Topology

A randomized controlled trial of 72 individuals with internet gaming disorder found that progressive aerobic training (PAT) over one month significantly reduced gaming severity, craving, and DSM-5 symptom scores compared to free training controls. Neuroimaging analysis revealed PAT promoted increased cross-network integration in the default mode network, with changes in network connectivity correlating with symptom improvement.

StudiuAdicțiiÎncredere bună19.06.2026

A complementary perspective on the normality-disorder boundary in gaming disorder research

This viewpoint argues that while time spent gaming and mood regulation mechanisms should not alone constitute diagnostic criteria for gaming disorder, they provide clinically relevant information for assessment. Features like extended play duration and over-reliance on gaming for coping can indicate functional impairment and inform individualized treatment approaches without being diagnostic criteria themselves.

StudiuAdicțiiÎncredere înaltă19.06.2026

Medicaid Managed Care Plan Alignment With State Substance Use Disorder Treatment Coverage Requirements

This study examined 167 Medicaid managed care plans in 2021 and found significant gaps in alignment with state-mandated coverage requirements for substance use disorder treatment medications, with many plans inappropriately imposing prior authorization barriers. Alignment with state requirements was notably lower among plans operating in Republican-leaning states.

StudiuAdicțiiÎncredere înaltă19.06.2026

Gambling disorder as a risk factor for suicidal ideation in medical students

This observational study of 775 French medical students found that 15.9% reported recent suicidal ideation, with students having probable gambling disorder showing significantly higher prevalence (34%) compared to those without gambling problems. The research identifies gambling disorder as an underexplored behavioral addiction contributing to suicide risk among medical students, alongside established factors like depression and burnout.

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