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Autism + ADHD

La intersecția autism–ADHD.

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StudiuAutism + ADHDÎncredere bună21.06.2026

Long-term changes in behavioral addiction symptoms among adults with ADHD treated with methylphenidate

A one-year prospective study of 37 adults with ADHD found that methylphenidate treatment significantly reduced symptoms of internet, shopping, food, and sex addictions, with the proportion of patients having at least one behavioral addiction diagnosis decreasing from 51.4% to 35.1%. Changes in cognitive impulsivity, sluggish cognitive tempo, and mood/anxiety symptoms correlated moderately with improvements in internet addiction scores.

StudiuAutism + ADHDÎncredere înaltă21.06.2026

Effect of Educational Interventions on Psychiatrists' Adherence to Treatment Guidelines for Schizophrenia and Depression: A Multicenter Implementation Study

The EGUIDE project evaluated how educational lectures on clinical practice guidelines influenced 782 psychiatrists' treatment practices across 176 Japanese hospitals, comparing guideline adherence in over 11,000 patients with schizophrenia or major depressive disorder. Psychiatrists who participated in guideline education showed higher rates of guideline-recommended treatments including appropriate antipsychotic monotherapy and reduced unnecessary psychotropic co-prescriptions.

StudiuAutism + ADHDÎncredere bună20.06.2026

Validation of the 10-Item Depression, Anxiety and Stress Scale in Mild Traumatic Brain Injury Patients

This study evaluated the psychometric properties of the DASS-10 in 354 treatment-seeking adults with mild TBI, finding good fit to the Rasch model with high internal consistency and acceptable unidimensionality. Results support the DASS-10 as a reliable, brief screening tool for psychological distress in post-mild TBI outpatient populations.

StudiuAutism + ADHDÎncredere bună20.06.2026

Persistent psychiatric symptoms in apparently well-controlled epilepsy: case report

A case of a middle-aged woman with well-controlled epilepsy who presented with persistent anxiety, depression, and irritability despite adequate psychiatric medication (escitalopram, olanzapine). Investigation revealed temporal lobe epilepsy auras as the underlying cause, and adjustment of anti-seizure therapy with lacosamide resulted in complete symptom resolution and significant functional improvement.

StudiuAutism + ADHDÎncredere înaltă20.06.2026

Mental Health Problems in Traumatic Spinal Cord Injury Patients: An Umbrella Systematic Review

This umbrella systematic review synthesized 20 systematic reviews to assess the prevalence and correlates of mental illness in traumatic spinal cord injury patients, finding depression (up to 43%), PTSD (up to 62%), anxiety (27%), and hazardous alcohol use (≥50%) as major concerns. Common risk factors included pain, injury severity, low social support, and maladaptive coping, though evidence for effective interventions was limited.

StudiuAutism + ADHDÎncredere bună20.06.2026

CCR5 as a key modulator in neurocognitive disorders: mechanisms and therapeutic implications

This integrative review examines CCR5's role as a regulator of neuroinflammation and cognitive function across multiple neurodegenerative and acquired neurological conditions including Alzheimer's disease, Parkinson's disease, MS, TBI, and stroke. Both genetic and pharmacologic CCR5 inhibition show potential to reduce neuroinflammation and preserve cognitive function, though some evidence suggests context-dependent protective roles in certain conditions, highlighting therapeutic complexity.

StudiuAutism + ADHDÎncredere înaltă20.06.2026

Evaluation of NTG-EDSD Dementia Screening Tool in Adults with Down Syndrome

A cohort study of 54 adults with Down syndrome (age ≥40) evaluated the NTG-EDSD screening tool for dementia/mild cognitive impairment, testing various scoring thresholds for sensitivity and specificity. While the tool shows promise for initiating clinical conversations and identifying need for further evaluation, it lacks sufficient standalone diagnostic accuracy for reliable dementia screening in this population.

StudiuAutism + ADHDÎncredere bună20.06.2026

Comorbidity of Autism Spectrum Disorder and Personality Disorders with Eating Disorders, PTSD, and Somatic Symptom Disorder: Clinical Challenges and Treatment Implications

This clinical review examines the prevalence and mechanisms underlying comorbidity between autism spectrum disorder, eating disorders, and PTSD when occurring alongside personality disorders, noting that such combinations typically increase symptom severity and suicide risk. Evidence-based treatments exist but novel approaches are needed, with future research prioritizing ASD-personality disorder trajectories and trauma-informed interventions addressing emotion dysregulation and patient engagement.