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AVC și AIT

Accident vascular cerebral și recuperare, la orice vârstă.

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StudiuAVC și AITÎncredere bună21.06.2026

Non-alcoholic fatty liver disease as a predictor of recurrent ischemic stroke and transient ischemic attack in carotid atherosclerosis

This retrospective study of 742 patients with carotid atherosclerosis found that non-alcoholic fatty liver disease (NAFLD) is independently associated with increased risk of recurrent ischemic stroke or transient ischemic attack during follow-up. A combined predictive model incorporating NAFLD status, clinical variables, and carotid plaque characteristics demonstrated superior performance in identifying high-risk patients for secondary stroke events.

StudiuAVC și AITÎncredere bună21.06.2026

Ischemic stroke incidence following COVID-19 bivalent booster vaccination in adults 65 years and older

A retrospective cohort study examined ischemic stroke and transient ischemic attack cases within 21 days of COVID-19 bivalent Pfizer vaccination in Kaiser Permanente patients aged 65+, finding an incidence of 34.3 per 100,000. While a safety signal was detected requiring further investigation, the authors appropriately note that validation of any causal association between vaccination and stroke risk is needed before conclusions can be drawn.

StudiuAVC și AITÎncredere bună21.06.2026

Preventability of Ischemic Stroke and Transient Ischemic Attack in a Tertiary Care Center in Argentina

This retrospective study evaluated patients with acute ischemic stroke or transient ischemic attack to assess how many cases could have been prevented through better management of vascular risk factors such as hypertension, dyslipidemia, atrial fibrillation, and smoking. The researchers developed a 10-point preventability scale to classify the degree to which each event was avoidable based on the optimization of modifiable risk factors at presentation.

StudiuAVC și AITÎncredere bună21.06.2026

Statins' Effect on Quality of Life and Functioning in Older Stroke Patients: Systematic Review and Meta-Analysis

This systematic review evaluated 6 randomized controlled trials and 16 cohort studies (66,273 patients, mean age 65-79) examining statin use for secondary prevention after ischemic stroke or transient ischemic attack. Meta-analysis of cohort studies showed a positive association between statins and improved functioning, though individual trials had mixed results regarding quality of life, with significant methodological limitations noted across included studies.

StudiuAVC și AITÎncredere bună20.06.2026

Left Atrial Reservoir Strain as a Predictor of Cardioembolic Ischemic Stroke and Atrial Fibrillation

This retrospective study evaluated left atrial reservoir strain using echocardiography in 79 stroke/TIA patients without prior atrial fibrillation history to identify cardiac sources of emboli. Reduced reservoir strain was associated with cardioembolic stroke mechanisms and atrial fibrillation occurrence, suggesting it may aid in stroke risk stratification and AF detection.

StudiuAVC și AITÎncredere bună20.06.2026

Cerebrovascular Events and Associated Risk Factors in Cervical Fibromuscular Dysplasia: A Systematic Review and Meta-Analysis

This systematic review and meta-analysis examines the incidence and risk factors for cerebrovascular events (including stroke) in patients with cervical fibromuscular dysplasia, a non-atherosclerotic vascular condition affecting arterial walls. The study synthesizes evidence to characterize stroke risk and associated factors in this patient population.

StudiuAVC și AITÎncredere bună20.06.2026

Early diagnosis of transient ischemic attack using SERS-based artificial intelligence sensors

Researchers developed a surface-enhanced Raman scattering (SERS) detection platform coupled with machine learning algorithms to identify transient ischemic attacks (TIA) through inflammatory markers in serum. The system achieved 99.64% accuracy using LightGBM and demonstrated robust performance across multiple deep learning models (>90% accuracy), with results validated against clinical diagnoses.

StudiuAVC și AITÎncredere bună20.06.2026

Protein Biomarkers for Distinguishing Acute Ischemic Stroke from Transient Ischemic Attack: A Meta-Analysis

This meta-analysis examined ten protein biomarkers across 18,160 acute ischemic stroke (AIS) and 3,410 transient ischemic attack (TIA) patients to identify biomarkers that could improve diagnostic differentiation between these two conditions. Five biomarkers showed statistically significant differences between AIS and TIA groups: S100B, sNfl, copeptin, IL-6, and MMP-9, with MMP-9 demonstrating the largest concentration differential.

StudiuAVC și AITÎncredere înaltă20.06.2026

Cerebrovascular Events After Head and Neck Radiation Therapy: Systematic Review and Meta-Analysis

This systematic review and meta-analysis of 50 studies demonstrates that head and neck cancer patients receiving radiation therapy have a significantly increased risk of ischemic stroke (8.98 per 1,000 person-years) and carotid stenosis compared to surgical or non-treated populations. The relative risk of stroke is approximately 1.3 times higher in irradiated patients, with carotid stenosis incidence ranging from 0-40% depending on follow-up duration.

StudiuAVC și AITÎncredere înaltă20.06.2026

Beyond Anticoagulation: Understanding Medical Therapy Failure in PFO-Related Stroke and the Case for Closure

This narrative review examines why anticoagulation fails in some patients with patent foramen ovale (PFO)-related cryptogenic stroke, synthesizing evidence showing transcatheter closure is superior to medical therapy in appropriately selected patients. The analysis incorporates pathophysiological mechanisms, randomized trial comparisons, and risk stratification tools (RoPE score, PASCAL classification) to guide optimal therapeutic selection.

StudiuAVC și AITÎncredere bună20.06.2026

Pre-stroke sleep quality predicts 1-year mortality and functional outcomes in ischemic stroke and TIA patients

This cohort study of 2,266 stroke/TIA patients found that poor pre-stroke subjective sleep quality (highest PSQI quartile) significantly increased 1-year mortality risk (3.73-fold) and poor functional outcome risk (2.15-fold) compared to good sleep quality. The association remained independent after adjusting for confounders, suggesting sleep quality as a prognostic marker in acute ischemic stroke.

StudiuAVC și AITÎncredere bună20.06.2026

Cervicocerebral atherosclerosis and atrial fibrillation increase long-term mortality in ischemic stroke patients

This study of 406 acute ischemic stroke/TIA patients found that atrial fibrillation combined with high cervicocerebral atherosclerotic burden significantly increased 7-year mortality risk, with those having AF and high atherosclerosis burden facing approximately 3-fold greater mortality risk. The findings suggest that concurrent presence of these two vascular conditions substantially worsens long-term outcomes compared to either condition alone.

StudiuAVC și AITÎncredere bună20.06.2026

Expression of Concern: Ischemic Stroke and TIA Related to Vasculitis Secondary to Primary Sjögren's Syndrome

This is an expression of concern (editorial notice) regarding a previously published case series linking ischemic stroke and transient ischemic attack to large-vessel vasculitis complications of primary Sjögren's syndrome. The concern document does not appear to endorse or dispute the clinical relationship itself, but rather raises methodological or publication integrity questions about the original article.

StudiuAVC și AITÎncredere bună20.06.2026

Association Between TSH Level and Stroke Severity: A Cross-Sectional Study Using the Modified Rankin Scale

This cross-sectional study of 204 stroke patients examined the relationship between thyroid-stimulating hormone (TSH) levels and stroke severity measured by the modified Rankin scale. A statistically significant weak-to-moderate negative correlation was found between TSH levels and stroke disability during admission and discharge, suggesting thyroid dysfunction may influence stroke outcomes.

StudiuAVC și AITÎncredere bună20.06.2026

Post-discharge telephone follow-up for ischemic stroke survivors: implementing best practices at a comprehensive stroke center

This quality improvement project implemented standardized post-discharge telephone follow-up protocols for ischemic stroke and TIA patients using the JBI Evidence Implementation Framework, addressing barriers through a multidisciplinary approach with updated protocols and staff education. Results showed statistically significant improvements in compliance with evidence-based follow-up practices compared to baseline measurements.

StudiuAVC și AITÎncredere bună19.06.2026

Risk Factors for Parenchymal Hematoma in Hemorrhagic Transformation After Intra-Arterial Thrombectomy

This retrospective study of 296 acute ischemic stroke patients undergoing intra-arterial thrombectomy identified older age and severe white matter hyperintensities as independent risk factors for hemorrhagic transformation. Among patients who developed hemorrhagic transformation, atrial fibrillation, lower total cholesterol, and elevated erythrocyte sedimentation rate were associated with more severe parenchymal hematoma.

StudiuAVC și AITÎncredere bună19.06.2026

Serum Extracellular Vesicle MicroRNA Profiles as Biomarkers for Ischemic Stroke and Transient Ischemic Attack

This study identified altered microRNA profiles in serum extracellular vesicles that distinguish ischemic stroke and transient ischemic attack patients from controls, with let-7b-5p and let-7f-5p emerging as key diagnostic markers. Mechanistic analysis suggests these miRNAs regulate FOXO1 and BDNF pathways involved in ischemic injury, supporting their potential clinical utility for stroke diagnosis and severity stratification.