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Autism + ADHD

La intersecția autism–ADHD.

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StudiuAutism + ADHDÎncredere bună21.06.2026

Psychiatric Comorbidities in Functional Neurological Disorders and Psychogenic Non-Epileptic Seizures: Systematic Review and Policy Recommendations

This systematic review examines psychiatric comorbidities associated with Functional Neurological Disorders (FND) and Psychogenic Non-Epileptic Seizures (PNES), finding these are not autonomous conditions but develop alongside autism, borderline personality disorder, PTSD, and alexithymia. The authors propose a biopsychosocial model where early trauma, abuse, and neglect contribute to progressive neurological sensitivity, particularly in young female patients, and recommend improved assessment and integrated treatment policies.

StudiuAutism + ADHDÎncredere bună21.06.2026

Anxiety and Depression after Spinal Cord Injury: A Cross-Sectional Study

This study examined the prevalence of depression and anxiety in individuals with subacute and chronic spinal cord injury using validated psychological assessment tools (BDI and STAI scales). Results showed significant alterations in both depression and anxiety levels, with differences noted between subacute and chronic phases; early psychological assessment and intervention are recommended to prevent cognitive and mental health complications.

StudiuAutism + ADHDÎncredere bună21.06.2026

Depression and ADHD as predictors of exercise addiction: A cross-sectional study in frequent exercisers

This cross-sectional study of 173 frequent exercisers (>10 hours/week) examined relationships between depression, ADHD symptoms, and exercise addiction using standardized scales and regression analyses. Depressive and ADHD symptoms were significantly positively correlated with exercise addiction symptoms, with depression emerging as the stronger predictor after controlling for age and gender.

StudiuAutism + ADHDÎncredere înaltă21.06.2026

Infantile Spasms in Pediatric Down Syndrome: Neurobiological Mechanisms and Therapeutic Approaches

This review examines why infantile spasms commonly occur in Down syndrome by analyzing animal models (Ts65Dn and TcMAC21 mice) to identify abnormalities in brain excitation and inhibition, particularly involving GABA receptor dysfunction. The research provides insights into potential therapeutic targets by clarifying the neurobiological mechanisms underlying seizure predisposition in Down syndrome.

StudiuAutism + ADHDÎncredere înaltă21.06.2026

Effect of Educational Interventions on Psychiatrists' Adherence to Treatment Guidelines for Schizophrenia and Depression: A Multicenter Implementation Study

The EGUIDE project evaluated how educational lectures on clinical practice guidelines influenced 782 psychiatrists' treatment practices across 176 Japanese hospitals, comparing guideline adherence in over 11,000 patients with schizophrenia or major depressive disorder. Psychiatrists who participated in guideline education showed higher rates of guideline-recommended treatments including appropriate antipsychotic monotherapy and reduced unnecessary psychotropic co-prescriptions.

StudiuAutism + ADHDÎncredere înaltă20.06.2026

Mental Health Problems in Traumatic Spinal Cord Injury Patients: An Umbrella Systematic Review

This umbrella systematic review synthesized 20 systematic reviews to assess the prevalence and correlates of mental illness in traumatic spinal cord injury patients, finding depression (up to 43%), PTSD (up to 62%), anxiety (27%), and hazardous alcohol use (≥50%) as major concerns. Common risk factors included pain, injury severity, low social support, and maladaptive coping, though evidence for effective interventions was limited.

StudiuAutism + ADHDÎncredere bună20.06.2026

CCR5 as a key modulator in neurocognitive disorders: mechanisms and therapeutic implications

This integrative review examines CCR5's role as a regulator of neuroinflammation and cognitive function across multiple neurodegenerative and acquired neurological conditions including Alzheimer's disease, Parkinson's disease, MS, TBI, and stroke. Both genetic and pharmacologic CCR5 inhibition show potential to reduce neuroinflammation and preserve cognitive function, though some evidence suggests context-dependent protective roles in certain conditions, highlighting therapeutic complexity.

StudiuAutism + ADHDÎncredere bună20.06.2026

Comorbidity of Autism Spectrum Disorder and Personality Disorders with Eating Disorders, PTSD, and Somatic Symptom Disorder: Clinical Challenges and Treatment Implications

This clinical review examines the prevalence and mechanisms underlying comorbidity between autism spectrum disorder, eating disorders, and PTSD when occurring alongside personality disorders, noting that such combinations typically increase symptom severity and suicide risk. Evidence-based treatments exist but novel approaches are needed, with future research prioritizing ASD-personality disorder trajectories and trauma-informed interventions addressing emotion dysregulation and patient engagement.