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NeuroPsy InfoHub adună studii și articole verificate editorial despre sănătate mintală și afecțiuni neurologice — pentru pacienți, familii și specialiști.

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Sănătate mintală și neurodezvoltare

AutismSpectrul autist și particularitățile asociate.223 de articole
ADHDAtenție, impulsivitate și hiperactivitate.202 articole
Sindrom DownDezvoltare și sprijin pentru sindromul Down.57 de articole
AnxietateÎngrijorare excesivă, tensiune, atacuri de panică.73 de articole
DepresieTristețe persistentă, lipsa energiei și a motivației.106 articole
AdicțiiDependențe de substanțe și comportamentale.135 de articole

Afecțiuni neurologice

DemențeBoala Alzheimer și alte forme de demență.73 de articole
AVC și AITAccident vascular cerebral și recuperare, la orice vârstă.64 de articole
Leziuni medulareLeziuni medulare, paraplegie și tetraplegie.55 de articole
EpilepsieCrize epileptice și managementul lor.127 de articole
ParkinsonBoala Parkinson și tulburări de mișcare.64 de articole
Scleroză multiplăScleroza multiplă și viața cu aceasta.71 de articole
Traumatisme cranio-cerebraleTraumatisme cranio-cerebrale și recuperare.81 de articole

Articole și ghiduri recomandate

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StudiuSindrom DownÎncredere înaltă27.06.2026

Cancer Frequencies and Screening in Individuals With Down Syndrome: A Comprehensive Nationwide Cross-Sectional Analysis

This large German study of 46,362 individuals with Down syndrome found lower overall cancer prevalence compared to matched controls, but significantly elevated risks for hematologic malignancies and testicular cancer, while breast, digestive, and skin cancers were less frequent. Notably, individuals with Down syndrome participated in cancer screening programs at substantially lower rates, highlighting a gap in preventive care access and adherence.

StudiuSindrom DownÎncredere înaltă27.06.2026

Multiomics and proteomic insights into Alzheimer's disease biology in Down syndrome

This scientific review synthesizes findings from brain, cerebrospinal fluid, and blood-based proteomic studies to characterize molecular pathways underlying Alzheimer's disease in Down syndrome, with focus on disruption of proteostasis, mitochondrial function, and immune signaling. The analysis positions Down syndrome-associated Alzheimer's disease as a network-level disorder where amyloid and tau pathology interact with immune responses, providing insights applicable to broader Alzheimer's disease biology.

StudiuSindrom DownÎncredere bună27.06.2026

Necroptosis in Down Syndrome: Evidence from Animal Models and Human Brain Tissue

Researchers identified elevated necroptosis markers (RIPK1, RIPK3, MLKL, and lncRNA MEG) in brains of aged Ts65dn mice and post-mortem tissue from Down syndrome subjects, suggesting this controlled cell death pathway may contribute to neuronal loss in DS. These findings propose necroptosis as a potential therapeutic target for developing new treatments in Down syndrome.

StudiuSindrom DownÎncredere înaltă23.06.2026

Social Cognition Development in Children and Adolescents With Down Syndrome: A Scoping Review

This systematic scoping review of 40 peer-reviewed studies (2008-2024) examined social cognition development in children and adolescents with Down syndrome, finding that language is the primary factor influencing social cognitive development rather than age alone. Individuals with Down syndrome demonstrate challenges in social cognition and emotion processing compared to typical development, with the review calling for more longitudinal research to clarify developmental trajectories and inform educational and clinical interventions.

StudiuSindrom DownÎncredere înaltă22.06.2026

Functional Fitness Decline in Adults with Down Syndrome: A 12-Year Longitudinal Study

This longitudinal study tracked functional fitness changes in 66 adults with Down syndrome over 12 years, finding significant deterioration in static balance, shoulder flexibility, trunk strength, and aerobic capacity for both men and women. Results suggest that adults with Down syndrome experience accelerated aging in physical fitness, indicating the need for timely physical activity interventions.