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Autism + ADHD

La intersecția autism–ADHD.

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StudiuAutism + ADHDÎncredere bună01.07.2026

Anxiety Symptom Networks in Major Depressive Disorder and Bipolar Disorder: A Comparative Network Analysis

This cross-sectional study of 815 patients compared anxiety symptom networks between major depressive disorder (MDD) and bipolar disorder (BD) using the Beck Anxiety Inventory and network analysis techniques. While both conditions showed similar core anxiety symptoms (loss of control, choking sensations, breathing difficulties, unsteadiness, shakiness), MDD demonstrated stronger overall network connectivity than BD, suggesting different patterns of symptom interconnection despite comparable symptom profiles.

StudiuAutism + ADHDÎncredere bună01.07.2026

Cord Blood Acylcarnitine Profile and Risk of ADHD and Autism in Childhood: A Prospective Birth Cohort Study

This prospective study examined whether acylcarnitine levels in cord blood—metabolites reflecting mitochondrial fatty acid metabolism—predict childhood ADHD and autism risk in 995 children. Higher short-chain and long-chain acylcarnitines were associated with significantly increased odds of ADHD and autism, suggesting early metabolic biomarkers may identify neurodevelopmental risk.

StudiuAutism + ADHDÎncredere înaltă30.06.2026

Prevalence and Trends of Developmental Disabilities Among US Children and Adolescents Aged 3 to 17 Years From 2016 to 2024

This epidemiological study analyzed national survey data from 2016–2024 to examine prevalence trends in ADHD, autism spectrum disorder, learning disabilities, intellectual disability, and other developmental delays in US children aged 3–17 years. Results showed significant increases in ADHD, learning disabilities, and autism prevalence, with distinct age patterns, while intellectual disability remained stable, highlighting a growing public health challenge requiring enhanced early identification and research.

StudiuAutism + ADHDÎncredere înaltă27.06.2026

Validation of the German Parent-Report Anxiety Scale for Autistic Children: Addressing Diagnostic Overlap and Autism-Specific Anxiety Patterns

This validation study examined the German version of the Anxiety Scale for Children with Autism Spectrum Disorder-Parent Version (ASC-ASD-P) in 317 youth at an autism clinic, including 120 autistic children, demonstrating excellent internal consistency and convergent validity with established behavioral measures. Autistic youth showed higher anxiety and uncertainty scores than non-autistic peers, confirming the scale's sensitivity to autism-specific anxiety presentations, though some subscales require refinement for broader applicability across the autism spectrum.

StudiuAutism + ADHDÎncredere înaltă26.06.2026

Agomelatine versus escitalopram for depression in people with epilepsy: A randomized controlled trial

This double-blind randomized trial compared agomelatine and escitalopram in 51 people with epilepsy and major depressive disorder, evaluating effects on depression, seizure frequency, sleep, cognition, and quality of life. Both medications improved depression similarly with minimal adverse events; escitalopram showed greater quality-of-life improvement while agomelatine showed better verbal memory outcomes, with no significant effects on seizure frequency in either group.

StudiuAutism + ADHDÎncredere bună26.06.2026

Symptomatic hyperprolactinemia mimicking pituitary pathology in a child with Landau-Kleffner syndrome and autism spectrum disorder: case report

A 12-year-old girl with autism spectrum disorder, Landau-Kleffner syndrome, and intellectual disability developed galactorrhea, vision problems, and falls while taking risperidone, with laboratory findings showing elevated prolactin (40.2 ng/mL) but normal imaging excluding pituitary tumor. Switching from risperidone to olanzapine resulted in complete symptom resolution and prolactin normalization (2.2 ng/mL) within three months, highlighting the importance of monitoring prolactin levels in children on antipsychotic medication.

StudiuAutism + ADHDÎncredere bună24.06.2026

Effect of Prior Depression Diagnosis on Bipolar Disorder Outcomes: A Retrospective Cohort Study

This retrospective cohort study analyzed 5,595 Japanese patients newly diagnosed with bipolar disorder to examine whether a prior depression diagnosis and its duration affected psychiatric and all-cause hospitalization rates and mortality. Patients with prior depression history showed slightly lower all-cause hospitalization risk (HR=0.87), with duration of preceding depression (≥1 year vs <1 year) not significantly altering psychiatric hospitalization outcomes.

StudiuAutism + ADHDÎncredere bună23.06.2026

Autism in Schizophrenia and Its Original Link to Self-Disorder: Returning a Borrowed Concept

This academic paper traces the historical origins of the term 'autism' coined by Eugen Bleuler in 1910 to describe schizophrenia, and how the concept was later borrowed to describe autism spectrum disorder, leading to diagnostic confusion. The authors argue that autistic features in schizophrenia differ fundamentally from autism spectrum disorder—rooted in self-disorder rather than developmental autism—and propose this distinction is crucial for accurate differential diagnosis and appropriate treatment.

StudiuAutism + ADHDÎncredere bună22.06.2026

Association Between Bipolar Disorder and Parkinson's Disease: A Review of Dopaminergic Mechanisms and Clinical Implications

This literature review examines the association between bipolar disorder and Parkinson's disease, focusing on their shared dopaminergic dysfunction in nigrostriatal and mesolimbic pathways. Recent analyses and meta-analyses show increased risk of developing Parkinson's disease in bipolar disorder patients, though differentiating idiopathic from medication-induced parkinsonism requires careful evaluation including DAT scans.

StudiuAutism + ADHDÎncredere înaltă22.06.2026

Formal and Informal Care Costs Following Traumatic Brain Injury and Spinal Cord Injury from Motor Vehicle Accidents: A Cross-Sectional Australian Study

This study compared the weekly utilization and associated costs of formal and informal care in 81 people with traumatic brain injury and 30 with spinal cord injury from motor vehicle accidents in Australia. Spinal cord injury (tetraplegia/paraplegia) required significantly higher costs for both formal and informal care, while informal care costs exceeded formal care costs for both conditions, highlighting the critical yet underacknowledged role of family caregiving in supporting recovery.

StudiuAutism + ADHDÎncredere bună22.06.2026

Attention and Behavioral Problems as Mediators of Internet Gaming Disorder in Youth With Family Addiction History

This study of 2,586 adolescents (ages 11-19) examined how attention problems and externalizing behaviors mediate the relationship between parental addiction history and internet gaming disorder. Higher attention and externalizing problems were significantly associated with IGD, with mediation analysis confirming these symptoms partially explain how family addiction history increases gaming disorder risk in youth.

StudiuAutism + ADHDÎncredere bună22.06.2026

Problematic Social Networking Site Use: Effects on Mental Health and Brain Function

Excessive social networking site use is associated with elevated rates of depression, anxiety, OCD, ADHD, and sleep disturbances, with preliminary neuroimaging evidence suggesting reduced gray matter in regions related to reward processing and inhibitory control. Cognitive Behavior Therapy shows promise as a short-term intervention, though more research is needed to fully understand the neurobiological mechanisms and treatment efficacy.

StudiuAutism + ADHDÎncredere înaltă22.06.2026

Mood instability and mental health service use in autism and ADHD: A natural language processing analysis of 21,906 children and adolescents

This study used natural language processing to analyze electronic health records from over 21,000 children with autism and/or ADHD, examining how baseline mood instability relates to mental health service use patterns. Mood instability was associated with significantly increased annual mental health service use across all diagnostic groups, with the strongest effects in ADHD alone, and reduced time to discharge specifically in the ADHD group.

StudiuAutism + ADHDÎncredere înaltă22.06.2026

Vaccine Hesitancy and Refusal in Parents of Children with Autism Spectrum Disorder and Developmental Delays: A Cross-Sectional Study

This study examined vaccine refusal rates among 154 parents of children with ASD or other developmental delays, finding that reported vaccine refusal increased from 3.9% before diagnosis to 9.7% after diagnosis, primarily driven by the false belief that vaccines caused their child's condition. The research documents the real public health harm from vaccine-autism misinformation while providing no scientific support for any vaccine-autism connection.

StudiuAutism + ADHDÎncredere înaltă21.06.2026

Epidemiological Study of Traumatic Brain and Spinal Injuries in Pediatric Patients: One-Year Analysis of Prevalence, Causes and Trends in Bulgaria

This retrospective study analyzed medical records of pediatric patients (under 18 years) admitted to a Bulgarian hospital emergency department over one year to determine prevalence, causes, and trends of traumatic brain and spinal cord injuries. Among 38,504 emergency department visits, 32% were children, with 0.3% hospitalized for neurosurgical conditions including TBI and SCI.

StudiuAutism + ADHDÎncredere bună21.06.2026

Relationship between depression and sex steroid hormones in women with epilepsy

This study investigated associations between sex steroid hormones, antiseizure medications, and depression in 112 women with epilepsy compared to 50 healthy controls, finding a 18.8% depression prevalence and significant hormonal differences including elevated testosterone and altered FSH, estradiol, progesterone, and prolactin levels. Sex steroid hormones emerge as potential biomarkers for depression risk in women with epilepsy, with implications for treatment and prognosis.

StudiuAutism + ADHDÎncredere bună21.06.2026

Neuropsychiatric Disorders and Burn Trauma: Clinical Epidemiology from a Tertiary Hospital

A prospective observational study over 24 months analyzed burn injury characteristics in patients with underlying neuropsychiatric conditions, finding epilepsy as the most common disorder (66.52%) followed by intellectual disability and dementia. Female patients experienced higher rates of severe burns and scalding injuries with more frequent third-degree burns and head/neck involvement compared to males.