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StudiuAVC și AITÎncredere bună19.06.2026

Risk Factors for Parenchymal Hematoma in Hemorrhagic Transformation After Intra-Arterial Thrombectomy

This retrospective study of 296 acute ischemic stroke patients undergoing intra-arterial thrombectomy identified older age and severe white matter hyperintensities as independent risk factors for hemorrhagic transformation. Among patients who developed hemorrhagic transformation, atrial fibrillation, lower total cholesterol, and elevated erythrocyte sedimentation rate were associated with more severe parenchymal hematoma.

StudiuAVC și AITÎncredere bună19.06.2026

Serum Extracellular Vesicle MicroRNA Profiles as Biomarkers for Ischemic Stroke and Transient Ischemic Attack

This study identified altered microRNA profiles in serum extracellular vesicles that distinguish ischemic stroke and transient ischemic attack patients from controls, with let-7b-5p and let-7f-5p emerging as key diagnostic markers. Mechanistic analysis suggests these miRNAs regulate FOXO1 and BDNF pathways involved in ischemic injury, supporting their potential clinical utility for stroke diagnosis and severity stratification.

StudiuAVC și AITÎncredere înaltă19.06.2026

Using radiological brain health to predict recurrence after ischemic stroke and transient ischemic attack: A population-based study

This population-based study examined whether neuroimaging markers of brain health could improve prediction of stroke recurrence beyond clinical factors alone using machine-learning techniques. Researchers followed 1,999 ischemic stroke and TIA patients from across 18 hospitals for 3 years, analyzing over 20 brain health measures on MRI to identify those at highest risk for recurrent stroke events.

StudiuAVC și AITÎncredere bună19.06.2026

Mechanical stress from hyoid bone as potential cause of ischemic stroke via carotid artery dissection: case report and systematic review

This case report describes a 46-year-old woman who experienced an acute ischemic stroke caused by internal carotid artery dissection, with imaging revealing direct contact between the dissected artery and the posterior horn of the hyoid bone. The authors argue that mechanical compression or microtrauma from hyoid bone anatomy may be a rare but identifiable anatomical risk factor for carotid dissection and subsequent stroke.

StudiuAVC și AITÎncredere bună19.06.2026

Multidimensional Study of Antiplatelet Therapy and CYP2C19 Genetic Testing in Ischemic Stroke and TIA Patients

This study evaluates current practices and guideline adherence for antiplatelet therapy and CYP2C19 genetic testing in stroke and TIA patients, combining systematic guideline review with retrospective analysis of 147 patients and physician interviews. Results show most patients received guideline-concordant empirical dual antiplatelet therapy, though genetic testing uptake was low, with recommendations for precision pharmaceutical care implementation.