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Altered prefrontal effective connectivity during emotion regulation in social anxiety disorder

This fMRI study used dynamic causal modelling to examine directed brain connectivity patterns during emotion regulation in 61 individuals with social anxiety disorder versus 41 healthy controls. Results revealed disrupted amygdala-prefrontal cortex communication in those with social anxiety, with reduced top-down modulation capacity during emotion regulation tasks.

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Epidemiology, Genetics, Neuroimaging, and Treatment of Social Anxiety Disorder: Comparing Overall and Performance-Only Presentations

This narrative review examines social anxiety disorder (SAD) across two presentations: overall SAD (5-13% prevalence) and performance-only SAD (0.3-0.7% prevalence), comparing their epidemiology, genetic factors, brain imaging patterns, and clinical outcomes. Performance-only SAD emerges later, affects fewer comorbidities, and shows more localized neural responses compared to overall SAD, which involves broader fronto-limbic network alterations and greater genetic influence.

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Predictors of Change in Treatment Response to Group-Based Cognitive Behavioral Therapy for Adolescents with Social Anxiety Disorder

This study examined baseline predictors of treatment response to group-based CBT in 90 adolescents (ages 12-17) with primary social anxiety disorder, evaluating demographic, clinical, and theory-derived factors. Results indicated that higher severity of safety behaviors and other maintaining factors predicted differential treatment outcomes at three-month follow-up.

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Psychometric Evaluation of the Severity Measure for Social Anxiety Disorder (SAD-DY) in Australian Adolescents

A community sample of 315 Australian adolescents completed the SAD-DY, a DSM-5-based social anxiety measure, demonstrating good internal consistency, concurrent validity, and discriminant validity through factor analysis. The study established criterion cut-off scores for both the 10-item and a newly developed 6-item abbreviated version (SAD-DY6), enhancing clinical utility for research and practice.