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Sindrom Down

Dezvoltare și sprijin pentru sindromul Down.

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StudiuSindrom DownÎncredere înaltă20.06.2026

Hypercalcemia of Down Syndrome: A Rare Metabolic Complication

This case report documents severe hypercalcemia with nephrocalcinosis in a 12-month-old with Down syndrome, successfully managed with intravenous fluids, calcitonin, and long-term dietary calcium restriction. The authors emphasize the importance of recognizing this rare but significant association and the proposed hyperabsorptive intestinal mechanism underlying the condition.

StudiuSindrom DownÎncredere înaltă20.06.2026

Alzheimer's disease in Down syndrome

Individuals with Down syndrome have significantly elevated risk for early-onset Alzheimer's disease due to the extra copy of chromosome 21, which contains the amyloid precursor protein gene. This condition represents a major health concern requiring specialized screening, management strategies, and caregiver support in this population.