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StudiuAVC și AITÎncredere înaltă21.06.2026

Comparison of American and European Guideline Recommendations for Diagnostic Workup and Secondary Prevention of Ischemic Stroke and Transient Ischemic Attack

This study compares stroke diagnostic and secondary prevention recommendations between American Heart Association/American Stroke Association (AHA/ASA) and European Stroke Organization (ESO) guidelines, analyzing 63 ESO and 82 AHA/ASA recommendations across 7 key topics. While most recommendations are similar, the guidelines assign different levels of evidence quality to many recommendations, with notable discrepancies in high-level evidence classifications.

StudiuAVC și AITÎncredere bună21.06.2026

Non-alcoholic fatty liver disease as a predictor of recurrent ischemic stroke and transient ischemic attack in carotid atherosclerosis

This retrospective study of 742 patients with carotid atherosclerosis found that non-alcoholic fatty liver disease (NAFLD) is independently associated with increased risk of recurrent ischemic stroke or transient ischemic attack during follow-up. A combined predictive model incorporating NAFLD status, clinical variables, and carotid plaque characteristics demonstrated superior performance in identifying high-risk patients for secondary stroke events.

StudiuAVC și AITÎncredere bună21.06.2026

Ischemic stroke incidence following COVID-19 bivalent booster vaccination in adults 65 years and older

A retrospective cohort study examined ischemic stroke and transient ischemic attack cases within 21 days of COVID-19 bivalent Pfizer vaccination in Kaiser Permanente patients aged 65+, finding an incidence of 34.3 per 100,000. While a safety signal was detected requiring further investigation, the authors appropriately note that validation of any causal association between vaccination and stroke risk is needed before conclusions can be drawn.

StudiuAVC și AITÎncredere bună21.06.2026

Preventability of Ischemic Stroke and Transient Ischemic Attack in a Tertiary Care Center in Argentina

This retrospective study evaluated patients with acute ischemic stroke or transient ischemic attack to assess how many cases could have been prevented through better management of vascular risk factors such as hypertension, dyslipidemia, atrial fibrillation, and smoking. The researchers developed a 10-point preventability scale to classify the degree to which each event was avoidable based on the optimization of modifiable risk factors at presentation.

StudiuAVC și AITÎncredere bună21.06.2026

Statins' Effect on Quality of Life and Functioning in Older Stroke Patients: Systematic Review and Meta-Analysis

This systematic review evaluated 6 randomized controlled trials and 16 cohort studies (66,273 patients, mean age 65-79) examining statin use for secondary prevention after ischemic stroke or transient ischemic attack. Meta-analysis of cohort studies showed a positive association between statins and improved functioning, though individual trials had mixed results regarding quality of life, with significant methodological limitations noted across included studies.