NeuroPsy InfoHub — informație de încredere despre neurodiversitate

Articole și ghiduri recomandate

VârstăToate vârstele Copii Tineri Adulți Vârstnici

StudiuDemențeÎncredere înaltă22.06.2026

Proteome-wide Analysis Identifies Cortical Proteins Associated with Cognitive Resilience in Aging and Dementia

This postmortem proteomics study of 604 older adults identified 47 cortical proteins in the dorsolateral prefrontal cortex that promote cognitive resilience across different cognitive domains, using mass spectrometry analysis while controlling for Alzheimer disease and related dementia pathologies. The protein NRN1 showed the strongest association, linked to multiple cognitive abilities including semantic memory, suggesting a potential role in protecting against dementia-related cognitive decline.

StudiuDemențeÎncredere bună22.06.2026

Deep Brain Stimulation for Cognitive Decline in Alzheimer Disease: Systematic Review of Clinical Evidence and Target Sites

A systematic review of 14 human studies (1994–2023) examined deep brain stimulation (DBS) targeting three brain regions to slow cognitive decline in Alzheimer disease. The fornix and nucleus basalis of Meynert showed promise in slowing decline according to standardized cognitive scales, though sample sizes were modest and long-term efficacy remains to be established.

StudiuDemențeÎncredere înaltă21.06.2026

Media Representations of Novel Alzheimer's Disease Treatments: Balancing Benefits and Risks

This study analyzes how major US newspapers portrayed disease-modifying treatments (DMTs) for Alzheimer's disease between 2020-2024, finding that media coverage linked treatment risks primarily to efficacy-to-cost ratios. The research identifies tensions between FDA regulatory challenges, expert disagreement over evidence quality, and patient expectations regarding these novel therapies.

StudiuDemențeÎncredere bună21.06.2026

Virtual Reality Interventions for Cognitive Function in Alzheimer's Disease: A Systematic Review and Meta-Analysis

This systematic review and meta-analysis examined the effects of virtual reality interventions on cognitive function in people with Alzheimer's disease across three randomized controlled trials involving 75 participants. VR showed modest improvements in memory performance compared to usual treatment, but demonstrated little to no effect on executive function.

StudiuDemențeÎncredere înaltă21.06.2026

Neuropsychiatric Presentations of Common Dementia Syndromes: A Clinical Review for Primary Care

This review examines neuropsychiatric symptoms (NPS) across four major dementia syndromes—Alzheimer's disease, vascular dementia, Lewy body dementia, and frontotemporal dementia—highlighting that these symptoms often emerge early or even precede cognitive decline. The article provides clinical guidance for primary care teams to recognize prodromal neurodegenerative disease and initiate appropriate diagnostic workup, addressing gaps in dementia training among frontline practitioners.

Informație de încredere. Sprijin real.

Explorează temele

Sănătate mintală și neurodezvoltare

Afecțiuni neurologice