NeuroPsy InfoHub adună studii și articole verificate editorial despre sănătate mintală și afecțiuni neurologice — pentru pacienți, familii și specialiști.
Hemispherotomy is a neurosurgical technique that disconnects one cerebral hemisphere to control severe, drug-resistant seizures in children following traumatic brain injury. This specialized intervention is considered when epilepsy originating from one hemisphere cannot be managed with medications, offering potential seizure control through anatomical brain disconnection rather than tissue removal.
This mechanistic review examines shared ion channel dysfunctions (particularly KCNQ1, KCNH2, SCN5A variants) that may simultaneously cause seizure susceptibility and cardiac repolarization abnormalities, proposing an integrated 'cardio-cerebral ion channelopathy' framework for understanding SUDEP risk. The authors discuss critical implications for anti-seizure medication safety assessment and precision medicine strategies in patients with overlapping neurological and cardiac vulnerability.
This study examines patterns of brain electrical synchronization during seizures using EEG network analysis with methods that generalize across different patients. The research contributes to understanding the neurophysiological mechanisms underlying seizure propagation and may inform clinical assessment or treatment approaches.
This cross-sectional study validated a self-report questionnaire (EST-Q) to assess perceived seizure triggers in 100 adults with epilepsy from Brazil. The seven-item core module showed adequate internal consistency for group-level research but insufficient reliability for individual clinical decisions, with exploratory factor analysis supporting a predominantly unidimensional structure.
Focal impaired awareness seizures (formerly complex partial seizures) originating in the temporal lobe frequently present with psychiatric symptoms including behavioral and affective disturbances, with peak incidence in elderly populations. This case report describes an older adult whose transient psychosis was ultimately attributed to seizure activity rather than primary psychiatric illness, highlighting the diagnostic challenge of recognizing seizure-related psychosis in geriatric patients.