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StudiuAdicțiiÎncredere bună19.06.2026

Case Report: Acamprosate Treatment for Volatile Hydrocarbon Inhalant Use Disorder with Comorbid Alcohol Use Disorder

A 39-year-old male with escalating volatile hydrocarbon inhalant use (computer duster) and comorbid alcohol use disorder was treated with acamprosate, a medication approved for alcohol use disorder, based on shared glutamatergic and GABAergic pathways. The case suggests acamprosate may warrant further investigation as a potential pharmacotherapy for inhalant use disorder, an understudied substance use condition.

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Machine Learning Applications in Alcohol Research: A Systematic Review of Current Methods and Clinical Potential

This systematic review examines machine learning approaches applied to alcohol-related outcomes across 110 peer-reviewed studies published 2015–2025, focusing on predictions of alcohol consumption and alcohol use disorder diagnosis. The authors identify that most studies use single-modality data and conventional machine learning techniques, highlighting opportunities to advance personalized medicine for AUD through overcoming current methodological limitations.

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Daily Stress and Gaming Patterns: An Ambulatory Assessment Study of Pathological, Risky, and Non-Problematic Gaming Behavior

This study examined the relationship between daily stress and gaming usage in 186 individuals categorized by gaming disorder severity (pathological, risky, non-problematic) using 14-day ambulatory assessment. Contrary to expectations, daily stress negatively predicted gaming usage and time, suggesting individuals may reduce gaming on high-stress days to manage competing demands, though social motives and symptom severity remained positive predictors.

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Global Review of Online Video Gaming Policies for Young People: Effectiveness of Age Ratings, Time Restrictions, and Loot Box Regulations

This systematic review evaluates worldwide policies regulating online video gaming for youth, examining age rating systems, gameplay time restrictions, and regulations on gambling-like mechanics (loot boxes). The findings indicate that while age ratings are widely implemented, compliance is poor; time restrictions are easily circumvented; and loot box regulations lack adequate enforcement, leaving consumer protection gaps that require stricter oversight and ongoing research.

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Elevated risk of alcohol use disorder in Japanese men living with HIV: Psychosocial determinants and protective role of sense of coherence

This cross-sectional study of 883 Japanese men living with HIV found that 53.2% engaged in at-risk or suspected alcohol use disorder, with heterosexual orientation, higher education, and older age associated with lower risk. Higher sense of coherence—the ability to cope with stress—emerged as a significant protective psychosocial factor against both at-risk drinking and suspected AUD.