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This prospective study tracked 520 individuals with first-episode psychosis over 478 days and found that 2.6 per 100 person-years developed problem gambling, with risk factors including white ethnicity, stimulant use disorder, lower education, and aripiprazole treatment. The findings highlight problem gambling as an underrecognized comorbidity in early psychosis that warrants clinical attention and monitoring.

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Internet Gaming Disorder Prevalence Among Individuals with Autism Spectrum Disorder in Saudi Arabia: A Comparative Study

This cross-sectional study examined the prevalence of Internet Gaming Disorder (IGD) in 276 parents of children with ASD in Riyadh, using the validated Internet Gaming Disorder Scale. IGD prevalence was 44.56% overall, with significant variations by age (27.27% in ages 6–12, 62.22% in ages 12–18, and 42.20% in ages >18) and sex differences noted between males and females.

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Circadian Rest-Activity Rhythms, Cognition, and Alzheimer Disease Dementia in Adults With Down Syndrome

This cross-sectional study investigates whether disruptions in 24-hour rest-activity rhythms are associated with cognitive impairment and Alzheimer disease status in adults with Down syndrome using wrist actigraphy and validated cognitive assessments. The research employs rigorous statistical methods and controls for confounding variables including age, sex, intellectual disability level, and sleep apnea severity.

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Practice Patterns and Barriers in Assessing and Treating Autism Spectrum Disorder in Children With Down Syndrome

This study surveyed clinicians across specialties to identify barriers in diagnosing autism spectrum disorder in individuals with Down syndrome, where dual diagnosis (DS+ASD) occurs in 16-18% of cases but is often delayed. Results show most clinicians recognize that ASD diagnosis significantly impacts management, but challenges include limited access to specialized diagnostic evaluations and communication/behavioral difficulties that complicate assessment.