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This study examines glial fibrillary acidic protein (GFAP) as a potential biomarker for visuospatial cognitive abilities in individuals with Down syndrome. The research explores the relationship between this neurobiological marker and specific neurocognitive outcomes in this population.
This multicenter study developed and piloted a Down syndrome-specific musculoskeletal screening tool to identify inflammatory arthritis (DA) in individuals with DS, finding a 2% confirmed diagnosis rate among positive screens. The tool is simple and feasible for clinical use, with symptoms of joint swelling, redness, warmth, and stiffness being most predictive of DA.
This retrospective study evaluated surgical outcomes for strabismus correction in 37 Down syndrome patients across esotropia, fourth nerve palsy, and mixed strabismus groups. Overall surgical success rates ranged from 40-86% depending on strabismus type, with 73% of cases achieving correction with a single procedure.
Study examining abnormal high-frequency brain oscillations occurring during sleep in individuals with Down syndrome. Research likely aims to characterize neurophysiological differences and their potential relationship to cognitive and developmental outcomes.
This study examines longitudinal screening approaches and population-level health strategies to enable earlier identification of Alzheimer's disease in individuals with Down syndrome. The research focuses on preventive detection methods and systematic screening protocols for this high-risk population.