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Sănătate mintală și neurodezvoltare

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Afecțiuni neurologice

DemențeBoala Alzheimer și alte forme de demență.73 de articole
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StudiuLeziuni medulareÎncredere bună22.06.2026

Reliability of five-minute versus one-hour heart rate variability metrics in individuals with spinal cord injury

This study evaluated the test-retest reliability of heart rate variability (HRV) measurements in 37 people with spinal cord injury, comparing 5-minute and 1-hour recordings taken in a supine position. Results showed that 1-hour recordings provided better reliability across multiple HRV parameters (intraclass correlations 0.13-0.71) compared to 5-minute recordings, with participants with tetraplegia demonstrating lower overall reliability.

StudiuLeziuni medulareÎncredere bună22.06.2026

Early Diagnosis of Late-Onset Neuropathic Pain in an Elderly Incomplete Tetraplegic Patient: A Charcot Spinal Arthropathy Case Report

This case report describes an 83-year-old tetraplegic man diagnosed with Charcot spinal arthropathy (neuropathic joint degeneration) after 3 years, earlier than typical presentations which average 17+ years after neurological injury. The condition results from impaired proprioception and sensation in the spine following central/peripheral nervous system damage, leading to progressive vertebral joint degeneration and instability.

StudiuLeziuni medulareÎncredere înaltă22.06.2026

Traumatic Spinal Cord Injury: Limitations of Single-Treatment Approaches and Need for Combined Therapeutic Strategies

This review examines decades of experimental and clinical research on traumatic spinal cord injury, concluding that single-treatment interventions (medications, growth factors, cell transplants) have produced only modest clinical improvements despite significant animal model results. The authors argue that effective rehabilitation requires moving beyond isolated therapeutic approaches to explore combined strategies targeting multiple secondary injury mechanisms.

StudiuLeziuni medulareÎncredere bună22.06.2026

Perceived Benefits of Spinal Cord Rehabilitation in Low-Middle Income Countries: A Qualitative Study

This qualitative study assessed 16 participants with chronic motor-incomplete tetraplegia enrolled in a 24-week rehabilitation pilot RCT in South Africa, comparing robotic locomotor training with standard activity-based training. Participants reported improvements in functional independence, reduced secondary complications, and enhanced psychosocial well-being, highlighting the importance of patient-centered approaches in SCI rehabilitation.

StudiuLeziuni medulareÎncredere înaltă21.06.2026

Epidemiology of pediatric spinal trauma with neurological deficits in Catalonia: a 36-year experience

A retrospective study of 249 children (mean age 13.9 years) with post-traumatic spinal cord injury admitted to a Catalan hospital between 1986-2022, documenting fracture types, locations, associated injuries, and neurological status using standardized assessment scales. Findings showed 82% had vertebral fractures, 43.4% had multilevel injuries, and 45% had associated injuries to limbs, thorax, abdomen or skull.