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Efficient EEG Channel-and-Frequency-Band Selection for Epileptic Seizure Classification Using Multi-Objective Optimization

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Folic acid supplementation and prevention of adverse offspring outcomes among women with epilepsy: An observational study

This multi-center Chinese cohort study of 1,013 women with epilepsy examined how folic acid supplementation affects pregnancy outcomes, finding that FA use in ASM-exposed pregnancies reduced risks of adverse composite outcomes and fetal death. Supplementation at ≥0.4 mg/day provided protection, with dose-response relationships analyzed using appropriate statistical models.

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Thyroid Function and Volume Changes in Children with Epilepsy Receiving Levetiracetam Monotherapy

A prospective study of 40 children on levetiracetam monotherapy found no significant changes in thyroid hormone levels or autoimmune markers over 6 months of treatment. Although thyroid volume standard deviation scores decreased slightly, absolute thyroid volume and thyroid function remained stable, suggesting levetiracetam does not adversely affect thyroid health in the short term.

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Classification of Epileptic Seizure Using Hybrid Deep Learning Framework with Time and Time-Frequency Hjorth Features

This study proposes a machine learning framework combining Hjorth parameters extracted from time and time-frequency domains with deep neural networks (CNN, BiLSTM, and attention mechanisms) to classify epileptic seizure stages. The approach achieved 98.4% accuracy for binary classification and 85.4% for five-class discrimination on the Bonn EEG dataset using rigorous cross-validation.

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Hematological Adverse Reactions in Epilepsy Patients: Monotherapy versus Polytherapy Comparison

This hospital-based study compared hematological parameters in 200 epilepsy patients receiving either single or multiple anti-seizure medications, finding that polytherapy was associated with different hematological profiles including variations in neutrophil counts, hemoglobin, and platelet indices. Certain blood parameters showed modest discriminatory ability for predicting treatment patterns, suggesting medication regimens may influence hematological outcomes in epilepsy.