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A cross-sectional study of 546 patients admitted with acute neurologic deficits identified 410 stroke cases (80% ischemic, 19% hemorrhagic) with 16% inpatient and 26% three-month mortality rates. Key findings included chronic kidney disease as a significant risk factor for hemorrhagic stroke and diabetes mellitus as a risk factor for both ischemic and hemorrhagic stroke types.
This article examines the relationship between autoimmune rheumatic diseases and increased stroke risk in affected patients. The content appears to address pathophysiological mechanisms and clinical implications of stroke complications in this patient population.
This study of 300 ischemic stroke patients found that elevated lipoprotein(a) (≥75 nmol/l) was associated with greater acute neurological deficits, longer hospital stays, and worse functional outcomes at discharge and 90 days. The findings suggest lipoprotein(a) may be relevant to stroke severity and recovery, though causality was not established.
A prospective cohort study of 1,261 stroke/TIA patients found that intracranial atherosclerotic stenosis (≥50% arterial narrowing) independently predicted cognitive impairment at 12 months, even after adjusting for other vascular risk factors and brain imaging markers. The association remained significant with cognitive impairment defined as Montreal Cognitive Assessment score <23.
This multicenter randomized controlled trial investigates whether home-based structured physical exercise combined with usual care reduces recurrent stroke risk in patients with symptomatic intracranial artery stenosis compared to usual care alone. The study enrolls 1,300 patients in China with primary outcomes measured at 1 year including recurrent ischemic stroke and secondary outcomes including transient ischemic attack and hemorrhagic stroke.