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Autism

Spectrul autist și particularitățile asociate.

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StudiuAutism + ADHDÎncredere bună20.06.2026

CCR5 as a key modulator in neurocognitive disorders: mechanisms and therapeutic implications

This integrative review examines CCR5's role as a regulator of neuroinflammation and cognitive function across multiple neurodegenerative and acquired neurological conditions including Alzheimer's disease, Parkinson's disease, MS, TBI, and stroke. Both genetic and pharmacologic CCR5 inhibition show potential to reduce neuroinflammation and preserve cognitive function, though some evidence suggests context-dependent protective roles in certain conditions, highlighting therapeutic complexity.

StudiuAutismÎncredere înaltă20.06.2026

Self-Regulation Domains in Autism, Down Syndrome, and Williams Syndrome: Transdiagnostic vs. Condition-Specific Patterns

This empirical study examined regulatory control across autism, Down syndrome, Williams syndrome, and neurotypical development in 233 children aged 5–13 using parent-report questionnaires assessing cognitive, emotional, social, and sensory regulation. Findings revealed both shared regulatory challenges across neurodiverse groups and condition-specific differences, with cluster analyses suggesting that regulatory profiles rather than diagnostic labels better predict support needs.

StudiuAutism + ADHDÎncredere bună20.06.2026

Comorbidity of Autism Spectrum Disorder and Personality Disorders with Eating Disorders, PTSD, and Somatic Symptom Disorder: Clinical Challenges and Treatment Implications

This clinical review examines the prevalence and mechanisms underlying comorbidity between autism spectrum disorder, eating disorders, and PTSD when occurring alongside personality disorders, noting that such combinations typically increase symptom severity and suicide risk. Evidence-based treatments exist but novel approaches are needed, with future research prioritizing ASD-personality disorder trajectories and trauma-informed interventions addressing emotion dysregulation and patient engagement.