Autentificare
NeuroPsy InfoHubÎnțelege · Sprijin · ProgresCere sprijin
← Toate temele

Autism

Spectrul autist și particularitățile asociate.

223 de articole
← Toate secțiunile

Studii și știri

PublicToțiPentru oricineSpecialiști
VârstăToate vârsteleCopiiTineriAdulțiVârstnici
StudiuAutismÎncredere bună26.06.2026

Assessment of Knowledge, Attitudes, and Behaviors Regarding Autism Spectrum Disorder Among Sixth-Year Medical Students in Izmir

This cross-sectional study evaluated 748 medical students in Turkish universities using validated questionnaires to assess their knowledge about ASD and societal attitudes toward autism. Results showed that while two-thirds attended ASD training, 39.4% lacked confidence in managing suspected ASD cases, and students with prior clinical experience or personal connections to individuals with ASD demonstrated significantly better knowledge and more positive attitudes.

StudiuAutismÎncredere bună26.06.2026

Biochemical Biomarker Profiles in Peripheral Blood of Valproic Acid-Induced Autism Model Rats Across Development

This experimental study investigated developmental changes in peripheral blood biomarkers (BDNF, neurotrophins, cytokines, serotonin) in rats with autism-like features induced prenatally using valproic acid and poly I:C. Behavioral screening confirmed autism phenotypes, and blood samples were analyzed at 2, 4, 6, and 8 weeks of age to characterize biochemical alterations.

PresăAutismÎncredere bună25.06.2026

Dogs May Bridge the Autism Drug Discovery Gap

Shank3 mutant beagles represent a potentially valuable preclinical model for autism research due to their naturally evolved social behaviors that more closely resemble human autism phenotypes than rodent models. This approach aims to address the high failure rate in translating autism drug candidates from animal studies to human clinical trials.

StudiuAutism + ADHDÎncredere bună24.06.2026

Effect of Prior Depression Diagnosis on Bipolar Disorder Outcomes: A Retrospective Cohort Study

This retrospective cohort study analyzed 5,595 Japanese patients newly diagnosed with bipolar disorder to examine whether a prior depression diagnosis and its duration affected psychiatric and all-cause hospitalization rates and mortality. Patients with prior depression history showed slightly lower all-cause hospitalization risk (HR=0.87), with duration of preceding depression (≥1 year vs <1 year) not significantly altering psychiatric hospitalization outcomes.

StudiuAutismÎncredere înaltă23.06.2026

Association between autism and psychosis: Systematic review and meta-analysis of measurement tools

This meta-analysis of 63 studies (N=6.9 million) found significant associations between autism and psychosis-spectrum traits across multiple dimensions, with individuals having one condition showing increased risk of being diagnosed with the other. The research highlights that measurement validity and potential misinterpretation of psychosis questionnaires by autistic individuals and clinicians may contribute to these associations.

StudiuAutism + ADHDÎncredere bună23.06.2026

Autism in Schizophrenia and Its Original Link to Self-Disorder: Returning a Borrowed Concept

This academic paper traces the historical origins of the term 'autism' coined by Eugen Bleuler in 1910 to describe schizophrenia, and how the concept was later borrowed to describe autism spectrum disorder, leading to diagnostic confusion. The authors argue that autistic features in schizophrenia differ fundamentally from autism spectrum disorder—rooted in self-disorder rather than developmental autism—and propose this distinction is crucial for accurate differential diagnosis and appropriate treatment.

StudiuAutism + ADHDÎncredere bună22.06.2026

Association Between Bipolar Disorder and Parkinson's Disease: A Review of Dopaminergic Mechanisms and Clinical Implications

This literature review examines the association between bipolar disorder and Parkinson's disease, focusing on their shared dopaminergic dysfunction in nigrostriatal and mesolimbic pathways. Recent analyses and meta-analyses show increased risk of developing Parkinson's disease in bipolar disorder patients, though differentiating idiopathic from medication-induced parkinsonism requires careful evaluation including DAT scans.

StudiuAutism + ADHDÎncredere înaltă22.06.2026

Structural and Metabolic Correlates of Neuropsychological Profiles in Multiple System Atrophy and Parkinson's Disease

This comparative neuroimaging study examined cognitive impairment in 11 patients with multiple system atrophy with parkinsonism (MSA-P) and 11 with Parkinson's disease using neuropsychological testing, diffusion tensor imaging, and PET imaging. Findings showed MSA-P patients had greater executive dysfunction and higher depression/anxiety scores, with specific correlations between cognitive performance and frontostriatal white matter integrity and glucose metabolism in both conditions.

StudiuAutism + ADHDÎncredere înaltă22.06.2026

Formal and Informal Care Costs Following Traumatic Brain Injury and Spinal Cord Injury from Motor Vehicle Accidents: A Cross-Sectional Australian Study

This study compared the weekly utilization and associated costs of formal and informal care in 81 people with traumatic brain injury and 30 with spinal cord injury from motor vehicle accidents in Australia. Spinal cord injury (tetraplegia/paraplegia) required significantly higher costs for both formal and informal care, while informal care costs exceeded formal care costs for both conditions, highlighting the critical yet underacknowledged role of family caregiving in supporting recovery.

StudiuAutism + ADHDÎncredere bună22.06.2026

Problematic Social Networking Site Use: Effects on Mental Health and Brain Function

Excessive social networking site use is associated with elevated rates of depression, anxiety, OCD, ADHD, and sleep disturbances, with preliminary neuroimaging evidence suggesting reduced gray matter in regions related to reward processing and inhibitory control. Cognitive Behavior Therapy shows promise as a short-term intervention, though more research is needed to fully understand the neurobiological mechanisms and treatment efficacy.

StudiuAutismÎncredere înaltă22.06.2026

Male-Biased Social Deficits in Chd8+/R2219* Mouse Model of Autism Linked to Hippocampal Abnormalities

This preclinical study generated a CRISPR-Cas9 mouse model carrying a CHD8 mutation associated with autism risk and found that male mice exhibited greater social deficits mirroring human sex bias, alongside macrocephaly and whole-brain enlargement. MRI and functional connectivity analyses revealed that hippocampal expansion and disrupted hippocampal network connectivity specifically correlated with social deficit severity in males, establishing hippocampal pathology as a key neural substrate for sex-biased autism phenotypes.

StudiuAutismÎncredere bună22.06.2026

Emotion- and Region-Specific Gaze Differences in Parents of Children With Autism Spectrum Disorder

A study using eyetracking compared visual attention patterns in parents of children with ASD versus parents of typically developing children while viewing emotional faces. Parents of children with ASD showed selective increased attention to the mouth region specifically when viewing threat-related emotions (anger, fear), suggesting emotion- and region-specific gaze allocation differences rather than generalized attentional changes.

StudiuAutismÎncredere bună22.06.2026

Cocoa polyphenols mitigate valproic acid-induced autism-like phenotypes in zebrafish via metabolic and proteomic mechanisms: a pilot study

This pilot study examined whether cocoa extract containing polyphenols could reverse autism-like behavioral and gastrointestinal abnormalities induced by valproic acid exposure in zebrafish. Cocoa co-treatment ameliorated hyperactivity and gut dysfunction while normalizing key metabolic and protein markers of cellular stress.

StudiuAutism + ADHDÎncredere bună21.06.2026

Relationship between depression and sex steroid hormones in women with epilepsy

This study investigated associations between sex steroid hormones, antiseizure medications, and depression in 112 women with epilepsy compared to 50 healthy controls, finding a 18.8% depression prevalence and significant hormonal differences including elevated testosterone and altered FSH, estradiol, progesterone, and prolactin levels. Sex steroid hormones emerge as potential biomarkers for depression risk in women with epilepsy, with implications for treatment and prognosis.

StudiuAutism + ADHDÎncredere bună21.06.2026

Neuropsychiatric Disorders and Burn Trauma: Clinical Epidemiology from a Tertiary Hospital

A prospective observational study over 24 months analyzed burn injury characteristics in patients with underlying neuropsychiatric conditions, finding epilepsy as the most common disorder (66.52%) followed by intellectual disability and dementia. Female patients experienced higher rates of severe burns and scalding injuries with more frequent third-degree burns and head/neck involvement compared to males.

StudiuAutism + ADHDÎncredere bună21.06.2026

Psychiatric Comorbidities in Functional Neurological Disorders and Psychogenic Non-Epileptic Seizures: Systematic Review and Policy Recommendations

This systematic review examines psychiatric comorbidities associated with Functional Neurological Disorders (FND) and Psychogenic Non-Epileptic Seizures (PNES), finding these are not autonomous conditions but develop alongside autism, borderline personality disorder, PTSD, and alexithymia. The authors propose a biopsychosocial model where early trauma, abuse, and neglect contribute to progressive neurological sensitivity, particularly in young female patients, and recommend improved assessment and integrated treatment policies.

StudiuAutism + ADHDÎncredere bună21.06.2026

Anxiety and Depression after Spinal Cord Injury: A Cross-Sectional Study

This study examined the prevalence of depression and anxiety in individuals with subacute and chronic spinal cord injury using validated psychological assessment tools (BDI and STAI scales). Results showed significant alterations in both depression and anxiety levels, with differences noted between subacute and chronic phases; early psychological assessment and intervention are recommended to prevent cognitive and mental health complications.