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Traumatisme cranio-cerebrale

Traumatisme cranio-cerebrale și recuperare.

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StudiuTraumatisme cranio-cerebraleÎncredere bună22.06.2026

Knowledge, Attitude, and Behavior of Medical Students Regarding Concussions: A Cross-Sectional Study

A cross-sectional study of 315 medical students in Saudi Arabia found that 68.3% demonstrated good knowledge about concussions as mild traumatic brain injuries, with 80.3% correctly recognizing the need to report symptoms to healthcare providers. However, misconceptions persisted, including the belief that all concussion patients require seven days of complete rest, highlighting gaps in clinical training despite overall adequate foundational understanding.

StudiuTraumatisme cranio-cerebraleÎncredere înaltă22.06.2026

Specialist Healthcare Services for Concussion/Mild Traumatic Brain Injury in England: A Consensus Statement

This consensus study used modified Delphi methodology with UK Head Injury Network specialists to establish evidence-based standards for concussion care structure and processes in England. Final consensus produced 18 statements covering care pathways, prognosis assessment, recovery measures, and outpatient clinic provision to improve healthcare quality and patient outcomes.

StudiuTraumatisme cranio-cerebraleÎncredere înaltă22.06.2026

Prognostic Value of CRASH and IMPACT Models for Predicting Mortality and Unfavorable Outcome in Traumatic Brain Injury: A Systematic Review and Meta-Analysis

This meta-analysis of 16 studies compared two widely-used prognostic models (CRASH and IMPACT) for predicting mortality and functional outcomes in traumatic brain injury patients. Both core models showed comparable predictive accuracy, with no significant differences in area under the curve for mortality or six-month unfavorable outcomes.

StudiuTraumatisme cranio-cerebraleÎncredere bună22.06.2026

Nutritional Interventions in Chronic Mild Traumatic Brain Injury and Concussion: A Systematic Review

This systematic review examined evidence for nutritional and dietary interventions in humans with chronic mild traumatic brain injury or concussion, identifying nine studies across six intervention types (omega-3 fatty acids, melatonin, Enzogenol, MLC901, ketogenic diet, phytocannabinoids). The review found these interventions to be safe and potentially beneficial for cognitive and sleep issues, but emphasized the paucity of human evidence and need for further research due to study heterogeneity.

StudiuTraumatisme cranio-cerebraleÎncredere înaltă22.06.2026

Clinical Updates in Mild Traumatic Brain Injury (Concussion)

This clinical review examines mild traumatic brain injury (concussion), which affects millions annually and is increasingly recognized as causing long-lasting functional deficits affecting work and social function. The article discusses epidemiology, common persistent symptoms, and evidence-based treatment strategies, emphasizing early recognition and risk identification for optimal recovery outcomes.

StudiuTraumatisme cranio-cerebraleÎncredere înaltă21.06.2026

Medical Coders' Perspectives on ICD-10-CM Coding Challenges for Head and Brain Injuries in Emergency Departments

This qualitative study examines how medical coders assign diagnostic codes to head and brain injuries in emergency department settings, identifying barriers to precise coding documentation. The research reveals that inadequate clinical documentation and time constraints in triage environments lead to frequent use of nonspecific injury codes, which affects the reliability of TBI surveillance data.

StudiuTraumatisme cranio-cerebraleÎncredere înaltă21.06.2026

History of biological, mechanistic, and clinical understanding of concussion

This review traces the evolution of concussion knowledge from the 10th century to modern times, highlighting Harrison Martland's 1928 postmortem studies of boxers that first documented structural brain changes underlying 'punch drunk' syndrome. The article examines how understanding of concussion's long-term consequences has progressed to include recognition of chronic traumatic encephalopathy (CTE) in athletes and military personnel, and discusses current preventative and therapeutic research directions.

StudiuTraumatisme cranio-cerebraleÎncredere bună21.06.2026

Convergence insufficiency as a predictor of poor prognosis after acute mild traumatic brain injury

This prospective study evaluated the feasibility of screening for convergence insufficiency (CI) symptoms in emergency department patients with mild traumatic brain injury using the Convergence Insufficiency Symptom Survey (CISS). Higher CISS scores were associated with adverse outcomes including post-concussive symptoms and hospital admission, suggesting oculomotor assessment may help identify patients at risk for poor recovery after mTBI.

StudiuTraumatisme cranio-cerebraleÎncredere bună21.06.2026

H4R antagonist JNJ-7777120 reduces traumatic brain injury damage via ERK1/2/NF-κB pathway inhibition in rats

This preclinical study demonstrates that JNJ-7777120, a histamine H4 receptor antagonist, improves motor and sensory function in rats with mild traumatic brain injury by reducing neuroinflammation, apoptosis, and oxidative stress. The neuroprotective effects occur through blockade of ERK1/2/NF-κB signaling pathways.

StudiuTraumatisme cranio-cerebraleÎncredere înaltă21.06.2026

Neurobehavioral Symptoms in Spanish-Speaking Individuals With Subconcussive Head Injuries

This cross-sectional study examined 709 Spanish-speaking adults (aged 18–65) to determine whether repeated head/neck injuries without loss of consciousness (subconcussive exposures) correlate with neurobehavioral symptoms. Results showed significant effects of both lifetime injury history and frequency of subconcussive exposure on symptom severity measured by the Neurobehavioral Symptom Inventory.

StudiuTraumatisme cranio-cerebraleÎncredere bună21.06.2026

Repetitive injury causes Alzheimer's disease-like phenotypes via reactivation of HSV-1 in a 3D human brain tissue model

This study demonstrates that repetitive traumatic brain injury can trigger reactivation of herpes simplex virus-1 (HSV-1) in human brain tissue, leading to pathological features characteristic of Alzheimer's disease. The research was conducted using advanced 3D brain tissue models, providing insights into potential mechanisms linking TBI to neurodegenerative disease risk.

StudiuTraumatisme cranio-cerebraleÎncredere bună21.06.2026

Fatigue and Sleep Disturbance After Traumatic Injury: Comparison of Those With and Without Mild Traumatic Brain Injury

This observational study of 110 traumatically injured individuals found that while fatigue and sleep disturbance were elevated compared to controls, these symptoms were not specifically attributable to mild traumatic brain injury itself. Rather, psychological distress and pain—common to all trauma survivors—were the primary predictors of fatigue and sleep disruption, regardless of head injury status.

StudiuTraumatisme cranio-cerebraleÎncredere bună21.06.2026

Psychological Interventions for Prolonged Post-Concussion Symptoms Beyond 12 Months: A Systematic Review

This systematic review evaluated the effectiveness of psychological interventions for prolonged post-concussion symptoms lasting more than 12 months after mild traumatic brain injury. Cognitive Behavioural Therapy showed the strongest evidence for improving anxiety, anger, and mental well-being, though the overall evidence base remains preliminary and requires more rigorous research.

StudiuTraumatisme cranio-cerebraleÎncredere bună21.06.2026

iPad-Based Neurocognitive Testing (ImPACT-QT) for Acute Adult Mild Traumatic Brain Injury: Feasibility and Bedside Cognitive Assessment in a Level-1 Trauma Center

This study evaluated the feasibility and utility of ImPACT-QT, a brief iPad-based cognitive screening tool, in acutely hospitalized trauma patients with mild TBI. The test was completed in ~9 minutes with high usability, and memory scores significantly differentiated mTBI patients from non-TBI controls, suggesting potential clinical utility for rapid bedside cognitive assessment.

StudiuTraumatisme cranio-cerebraleÎncredere înaltă20.06.2026

Prevalence of Headache Following Traumatic Brain Injury: A Systematic Review and Meta-Analysis

This systematic review and meta-analysis synthesized data from observational studies (2000-2024) to assess post-traumatic headache (PTH) prevalence in TBI patients, finding a pooled prevalence of 49.3%. Subgroup analyses revealed variations across measurement tools and study characteristics, with interviews reporting higher prevalence rates than other assessment methods.

StudiuTraumatisme cranio-cerebraleÎncredere înaltă20.06.2026

Hindi Adaptation and Psychometric Validation of Rivermead Post-Concussion Symptoms Questionnaire for Traumatic Brain Injury Patients

This study successfully adapted the Rivermead Post-Concussion Symptoms Questionnaire into Hindi and validated it for use in Hindi-speaking TBI patients. The Hindi version demonstrated good reliability, temporal stability, and a six-factor structure with adequate psychometric properties for assessing post-head injury symptoms.

StudiuTraumatisme cranio-cerebraleÎncredere bună20.06.2026

National audit of head injury discharge advice compliance with NICE guidelines

This audit evaluated 99 head injury discharge leaflets from NHS England trusts against NICE guidance (NG232), finding none achieved full compliance (mean score 0.42/1.0). While safety information about surgical deterioration met targets, advice on concussion symptom management and return-to-activity guidance fell significantly short of standards.