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ADHD

Atenție, impulsivitate și hiperactivitate.

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StudiuAutism + ADHDÎncredere bună26.06.2026

Symptomatic hyperprolactinemia mimicking pituitary pathology in a child with Landau-Kleffner syndrome and autism spectrum disorder: case report

A 12-year-old girl with autism spectrum disorder, Landau-Kleffner syndrome, and intellectual disability developed galactorrhea, vision problems, and falls while taking risperidone, with laboratory findings showing elevated prolactin (40.2 ng/mL) but normal imaging excluding pituitary tumor. Switching from risperidone to olanzapine resulted in complete symptom resolution and prolactin normalization (2.2 ng/mL) within three months, highlighting the importance of monitoring prolactin levels in children on antipsychotic medication.

PresăADHDÎncredere bună25.06.2026

Scientists discover ancient brain cells that help block distractions

Researchers identified neurons in an ancient brain region that function as a focus filter, enabling selective attention to relevant stimuli. Temporarily disabling these neurons in mice produced ADHD-like distractibility symptoms, which normalized upon reactivation, suggesting a biological mechanism underlying attention regulation.

StudiuADHDÎncredere bună25.06.2026

Efficacy and Safety of SPN-812 (Extended-Release Viloxazine) in Children and Adolescents with ADHD: A Systematic Review and Meta-Analysis

This meta-analysis of five randomized controlled trials involving 1,619 pediatric patients (ages 6-17) demonstrates that SPN-812 at doses of 100, 200, and 400 mg/day significantly improved ADHD symptoms compared to placebo on multiple validated rating scales. SPN-812 at 300 mg/day showed favorable safety profiles with no increased risk of serious adverse events like syncope, though higher doses were associated with increased somnolence and appetite suppression.

StudiuAutism + ADHDÎncredere bună24.06.2026

Effect of Prior Depression Diagnosis on Bipolar Disorder Outcomes: A Retrospective Cohort Study

This retrospective cohort study analyzed 5,595 Japanese patients newly diagnosed with bipolar disorder to examine whether a prior depression diagnosis and its duration affected psychiatric and all-cause hospitalization rates and mortality. Patients with prior depression history showed slightly lower all-cause hospitalization risk (HR=0.87), with duration of preceding depression (≥1 year vs <1 year) not significantly altering psychiatric hospitalization outcomes.

PresăADHDÎncredere bună23.06.2026

Ancient Brainstem Neurons Discovered to Control Attention

Researchers identified an evolutionarily conserved circuit of inhibitory neurons in the brainstem that regulates selective spatial attention. This discovery may enhance understanding of attention mechanisms relevant to conditions like ADHD.

StudiuAutism + ADHDÎncredere bună23.06.2026

Autism in Schizophrenia and Its Original Link to Self-Disorder: Returning a Borrowed Concept

This academic paper traces the historical origins of the term 'autism' coined by Eugen Bleuler in 1910 to describe schizophrenia, and how the concept was later borrowed to describe autism spectrum disorder, leading to diagnostic confusion. The authors argue that autistic features in schizophrenia differ fundamentally from autism spectrum disorder—rooted in self-disorder rather than developmental autism—and propose this distinction is crucial for accurate differential diagnosis and appropriate treatment.

StudiuAutism + ADHDÎncredere bună22.06.2026

Association Between Bipolar Disorder and Parkinson's Disease: A Review of Dopaminergic Mechanisms and Clinical Implications

This literature review examines the association between bipolar disorder and Parkinson's disease, focusing on their shared dopaminergic dysfunction in nigrostriatal and mesolimbic pathways. Recent analyses and meta-analyses show increased risk of developing Parkinson's disease in bipolar disorder patients, though differentiating idiopathic from medication-induced parkinsonism requires careful evaluation including DAT scans.

StudiuAutism + ADHDÎncredere înaltă22.06.2026

Structural and Metabolic Correlates of Neuropsychological Profiles in Multiple System Atrophy and Parkinson's Disease

This comparative neuroimaging study examined cognitive impairment in 11 patients with multiple system atrophy with parkinsonism (MSA-P) and 11 with Parkinson's disease using neuropsychological testing, diffusion tensor imaging, and PET imaging. Findings showed MSA-P patients had greater executive dysfunction and higher depression/anxiety scores, with specific correlations between cognitive performance and frontostriatal white matter integrity and glucose metabolism in both conditions.

StudiuAutism + ADHDÎncredere înaltă22.06.2026

Formal and Informal Care Costs Following Traumatic Brain Injury and Spinal Cord Injury from Motor Vehicle Accidents: A Cross-Sectional Australian Study

This study compared the weekly utilization and associated costs of formal and informal care in 81 people with traumatic brain injury and 30 with spinal cord injury from motor vehicle accidents in Australia. Spinal cord injury (tetraplegia/paraplegia) required significantly higher costs for both formal and informal care, while informal care costs exceeded formal care costs for both conditions, highlighting the critical yet underacknowledged role of family caregiving in supporting recovery.

StudiuAutism + ADHDÎncredere bună22.06.2026

Attention and Behavioral Problems as Mediators of Internet Gaming Disorder in Youth With Family Addiction History

This study of 2,586 adolescents (ages 11-19) examined how attention problems and externalizing behaviors mediate the relationship between parental addiction history and internet gaming disorder. Higher attention and externalizing problems were significantly associated with IGD, with mediation analysis confirming these symptoms partially explain how family addiction history increases gaming disorder risk in youth.

StudiuAutism + ADHDÎncredere bună22.06.2026

Problematic Social Networking Site Use: Effects on Mental Health and Brain Function

Excessive social networking site use is associated with elevated rates of depression, anxiety, OCD, ADHD, and sleep disturbances, with preliminary neuroimaging evidence suggesting reduced gray matter in regions related to reward processing and inhibitory control. Cognitive Behavior Therapy shows promise as a short-term intervention, though more research is needed to fully understand the neurobiological mechanisms and treatment efficacy.

StudiuADHDÎncredere bună22.06.2026

Emotional and Behavioral Effects of Online Self-Reflective Meditation in Youth With ADHD: A Randomized Clinical Trial

A 12-week randomized controlled trial of an online meditation program in 40 youth with ADHD found selective improvements in trait anxiety and some self-reported emotional symptoms, but no significant effects on observable behavioral problems or core attention deficits. The intervention showed modest promise as a complementary approach targeting emotional regulation rather than primary ADHD symptoms.

StudiuADHDÎncredere bună22.06.2026

Comorbid Psychiatric Symptoms as Mediators Between Childhood ADHD Symptoms and Functional Impairment in University Students

This study examined 110 university students with elevated ADHD symptoms to determine whether current psychiatric comorbidities (depression, anxiety) mediate the relationship between childhood ADHD symptoms and functional impairment across domains like family, social functioning, and self-concept. Results indicated that while childhood ADHD symptoms directly predicted family domain impairment, depressive and anxiety symptoms were stronger predictors of impairment in life skills, self-concept, and social functioning, with indirect pathways through comorbid symptoms confirmed.

StudiuADHDÎncredere bună22.06.2026

Paraben and Phthalate Exposure in Adolescents With ADHD: A Case-Control Study

This case-control study compared urinary concentrations of parabens and phthalate metabolites between 39 adolescents with clinically diagnosed ADHD and 41 healthy controls, finding differences in several chemical metabolites and an association between dimethyl phthalate and ADHD status. The study used validated laboratory methods and adjusted for socioeconomic and anthropometric factors, though the authors note that findings for compounds with low detection frequency should be interpreted cautiously.

StudiuAutism + ADHDÎncredere înaltă22.06.2026

Mood instability and mental health service use in autism and ADHD: A natural language processing analysis of 21,906 children and adolescents

This study used natural language processing to analyze electronic health records from over 21,000 children with autism and/or ADHD, examining how baseline mood instability relates to mental health service use patterns. Mood instability was associated with significantly increased annual mental health service use across all diagnostic groups, with the strongest effects in ADHD alone, and reduced time to discharge specifically in the ADHD group.

StudiuADHDÎncredere înaltă22.06.2026

Parent Profiles as Predictors of Emotion Dysregulation in Adolescents: ADHD vs. Non-ADHD Comparison

This study identified three distinct parenting profiles among 266 adolescents (51% with ADHD diagnosis) and examined their association with emotion dysregulation. Findings showed parents of adolescents with ADHD were more likely to exhibit high internalizing symptoms, emotion dysregulation, and moderate authoritative parenting compared to parents of non-ADHD peers.

StudiuAutism + ADHDÎncredere înaltă22.06.2026

Vaccine Hesitancy and Refusal in Parents of Children with Autism Spectrum Disorder and Developmental Delays: A Cross-Sectional Study

This study examined vaccine refusal rates among 154 parents of children with ASD or other developmental delays, finding that reported vaccine refusal increased from 3.9% before diagnosis to 9.7% after diagnosis, primarily driven by the false belief that vaccines caused their child's condition. The research documents the real public health harm from vaccine-autism misinformation while providing no scientific support for any vaccine-autism connection.