Dependențe de substanțe și comportamentale.
135 de articoleAn FDA-approved rheumatoid arthritis drug that blocks IL-6 receptors significantly reduced excessive alcohol consumption in alcohol-dependent female mice by suppressing neuroinflammation in the central amygdala. This mechanism aligns with elevated IL-6 expression observed in postmortem brain tissue from individuals with alcohol use disorder, suggesting a potential therapeutic target.
This neuroimaging study compared brain structural connectivity in 25 individuals with gambling disorder versus 28 healthy controls using diffusion tensor imaging and probabilistic tractography. The gambling disorder group showed increased striatal connectivity but reduced frontal lobe connectivity and fewer neural hubs, suggesting impaired network integration related to risk-taking control.
Gaming disorder, recognized by WHO and APA as a behavioral addiction, affects individuals who experience significant daily functioning impairment from excessive gaming. While moderate gaming offers benefits like stress relief and cognitive improvement, addiction is linked to psychological disorders requiring long-term treatment including cognitive behavioral therapy, making prevention efforts at government, developer, and household levels essential.
This research investigates theta burst stimulation, a neuromodulation technique, as a potential treatment for gambling disorder by measuring changes in craving intensity and relevant biological markers. The study examines whether this brain stimulation approach can reduce gambling cravings and identify associated neurobiological changes in affected patients.
This study examined how personality dimensions and impulsivity traits relate to problematic internet usage among 1,144 online MMORPG and poker players using validated psychological instruments. Neuroticism, negative urgency, positive urgency, and sensation seeking were significantly associated with higher addiction scores, while extraversion showed a protective effect, with similar patterns observed across both gaming groups.
This work examines the intersection of gambling disorder and legal accountability within the Brazilian justice system, analyzing how behavioral addiction affects criminal responsibility determinations. It addresses forensic and legal implications of recognizing gambling disorder as a behavioral addiction in criminal proceedings.
This study translated and adapted the Online Gambling Disorder Questionnaire (OGD-Q) for Brazilian Portuguese, examining its psychometric properties across 298 participants. The instrument demonstrated strong internal consistency (Cronbach's alpha 0.92) and significant correlations with depression, anxiety, stress, and online gaming behavior, supporting its validity as a screening tool for problematic online gambling.
This systematic review synthesizes 30 peer-reviewed studies on gambling disorder (GD) within couple relationships, examining its behavioral addiction features (craving, tolerance, withdrawal) and complex etiology. Research highlights how dysfunctional relational dynamics perpetuate GD, with studies documenting impacts on partners, links to domestic violence, and bidirectional relationships between couple dynamics and gambling behaviors.
This academic work examines methodological issues and systematic biases in the instruments used to assess gaming disorder. The study contributes to improving diagnostic accuracy and reliability of behavioral addiction measurement tools.
This retrospective study of 633 patients with alcohol or substance use disorders found that folate deficiency varies significantly by substance type, with methamphetamine users showing the lowest folate levels and highest folate deficiency rates. Alcohol, methamphetamine, and opioid users had significantly higher folate deficiency compared to cannabis users, highlighting the importance of nutritional assessment in substance use disorder treatment.
This clinical case explores the relationship between gambling disorder and elevated suicide risk, highlighting the severity of behavioral addiction and associated mental health complications. The presentation documents a real patient scenario illustrating how gambling addiction can co-occur with suicidal ideation and the importance of integrated psychiatric assessment.
This editorial examines the current state of scientific understanding regarding how addiction affects brain structure and function. It reviews established research methods and discusses emerging perspectives on studying addiction neurobiology.
This scoping review of 19 literature reviews documents that 20–51% of health professionals hold negative attitudes toward people with substance and non-substance use disorders, with negative stigma significantly impacting care quality. Addiction training, clinical experience, and adoption of the medical chronic disease model are identified as key factors that reduce stigmatization and improve professional engagement in addiction care.
This mixed-method study of 185 recovered gambling disorder individuals examined whether recovery involves substitution with other addictive behaviors or concurrent recovery across addictions. Substitution was primarily driven by using other substances/behaviors as coping mechanisms, while concurrent recovery occurred when addictions were mutually reinforcing; negative emotional states were common in both pathways.
This empirical study surveyed 431 Asian Americans to examine how public stigma and self-stigma affect willingness to seek mental health treatment for gambling and Internet gaming addictions. Findings indicate that self-stigma about help-seeking and public stigma attitudes significantly influence treatment-seeking behavior, with recommendations for culturally-informed community outreach to reduce barriers to mental health service utilization.
This narrative review examines whether Gaming Disorder can be diagnosed alongside bipolar disorder, specifically analyzing an ICD-11 exclusion criterion that restricts GD diagnosis when disordered gaming occurs only during manic/elevated mood episodes. The review synthesizes diagnostic criteria development and published studies to assess the validity of this exclusion criterion and proposes directions for future research on differential diagnosis between Gaming Disorder and pathological gambling.
This study assessed attitudes of 128 doctors and 785 nurses toward patients with alcohol use disorder using the validated Alcohol & Alcohol-Problems Perceptions Questionnaire. While most healthcare workers recognized the importance of intervention, they reported low confidence in their own competence, available support, and motivation to treat these patients, indicating need for institutional training programs.
This study investigates the frequency and patterns of concurrent gambling disorder among individuals with substance use disorders, exploring the relationship between these two behavioral/substance addictions. The research contributes to understanding shared neurobiological and psychological mechanisms underlying multiple addiction disorders.
