Dependențe de substanțe și comportamentale.
135 de articoleThis study investigates how impaired executive function and deficient decision-making processes relate to the development and progression of gambling disorder symptoms in individuals who engage in online sports betting. The research explores neuropsychological factors underlying problematic gambling behavior as a behavioral addiction.
This study analyzed genetic and social factors contributing to comorbid conditions in people with substance use disorders using data from 393,596 individuals. Polygenic scores for alcohol use, cannabis use, depression, and schizophrenia were significantly associated with time to subsequent diagnoses, while social determinants like low household income showed strong associations with lifetime SUD risk.
This study validated the Turkish translation of the SSBA, a screening tool assessing both substance-related and behavioral addictions across ten dimensions. The instrument demonstrated excellent internal consistency (α=0.94) and effectively distinguished between clinical and general populations, supporting its reliability for addiction assessment in clinical and research contexts.
This review examines mGluR2 (metabotropic glutamate receptor 2) as a promising molecular target for treating alcohol use disorder, which involves dysregulated glutamatergic neurotransmission. Preclinical evidence supports that mGluR2 agonists and positive allosteric modulators can reduce alcohol-seeking behaviors by restoring glutamatergic homeostasis.
This longitudinal study of 5,172 Finnish adults with gambling disorder found high co-occurrence with mood, anxiety, and substance use disorders, with bidirectional comorbidity patterns. Most psychiatric diagnoses preceded gambling disorder diagnosis by 112–2,697 days, with mood disorders more prominent in women and substance use disorders more common in men.
A Veterans Health Administration quality improvement pilot integrated behavioral health providers into hepatology clinics to engage patients with alcohol-associated liver disease in treatment. Referred patients showed significantly higher rates of evidence-based alcohol use disorder psychotherapy and pharmacotherapy within 6 months compared to non-referred patients.
This review traces how the understanding of addiction's neurobiological mechanisms has evolved across six editions of a major neuroscience textbook, from initial psychological theories to modern knowledge about dopamine, basal ganglia, and learning systems. The analysis demonstrates a conceptual shift from homeostatic models toward understanding addiction as a disorder of motivation, learning, and habit formation.
This study examined whether steroid hormones (testosterone and cortisol) measured from hair samples predict problematic pornography use in 252 men, using the dual-hormone hypothesis framework. Results showed testosterone positively associated with pornography use severity, with this effect moderated by cortisol levels—strongest at low cortisol and weakened at high cortisol.
This study examined 100 men with gambling disorder and 59 healthy controls using the Balloon Analog Risk Task and found that individuals with gambling disorder show paradoxical stronger initial loss aversion but faster decline in loss sensitivity over time. The faster-diminishing loss sensitivity was identified as a key cognitive mechanism explaining impaired risky decision-making in gambling disorder, alongside overconfident beliefs and elevated impulsiveness.
This systematic review identified 28 CBT studies across 22 interventions for gaming disorder, synthesizing common therapeutic practice elements through manual analysis and expert evaluation. The most frequently used components were emotion regulation skills training (95.5%), psychoeducation (90.9%), and cognitive restructuring (86.4%), with behavioral activation and relapse prevention appearing universally in individual therapy formats.
This bibliometric study analyzed 863 peer-reviewed articles to map the relationship between digital addiction (internet, smartphone, social media) and mental health outcomes across multiple research fields. Key findings identified anxiety disorder, depression, and sleep quality as primary mental health concerns associated with addictive digital device use, while highlighting underexplored populations and emerging research directions.
This study presents the development and validation of STEPS-IDD, a comprehensive screening tool designed to assess multiple addictive behaviors related to internet and digital device use according to WHO ICD-11 criteria, including gaming, gambling, social media, online shopping, and pornography use. The instrument underwent rigorous psychometric validation including face validity through expert review, construct validity via exploratory factor analysis, and internal consistency assessment, establishing it as a standardized tool for clinical and research use.
This secondary analysis of a randomized placebo-controlled trial examined predictors of treatment response in gambling disorder patients receiving intranasal naloxone plus psychosocial support. Medication adherence and readiness to change were strongly associated with improved outcomes including reduced gambling urges and better quality of life.
This systematic review examines gambling disorder as a behavioral addiction within the context of intimate partnerships and couple dynamics. The study synthesizes evidence on how gambling disorder affects relationship functioning, partner wellbeing, and intervention outcomes for affected couples.
This 18-year longitudinal study of 360 Swedish patients treated for severe alcohol withdrawal examined whether comorbid substance use, demographics, and the ANKK1 A1 allele predicted mortality outcomes. Male sex and age were the strongest predictors of early death in AUD patients, while poly-substance users showed higher psychiatric comorbidity and traumatic causes of death.
This study examined how different gambling motivations predict progression to more severe gambling disorder, analyzing whether these associations differ between men and women using DSM-5 severity criteria. Coping-related motives (forgetting worries, depression-triggered gambling) and financial motives consistently predicted greater disorder severity across genders, with limited gender-specific differences in motive effects.
This study examined occipital EEG patterns in 15 individuals with gaming disorder versus 15 controls during active mobile gaming, identifying spectral biomarkers including increased delta/theta power and decreased beta activity. Machine learning classification achieved 80% accuracy, suggesting altered attentional stability and neural habituation patterns in gaming disorder.
This study analyzed health insurance data from 3,154 adults with gambling disorder in Bavaria, finding that only 18.6% received psychotherapy despite evidence supporting its effectiveness. Patients receiving psychotherapy were younger and more likely female, with higher rates of comorbid depression and anxiety compared to those receiving only psychiatric/neurological care or no specialist treatment.