NeuroPsy InfoHub adună studii și articole verificate editorial despre sănătate mintală și afecțiuni neurologice — pentru pacienți, familii și specialiști.
Researchers at Texas A&M University developed a novel mouse model using Theiler's murine encephalomyelitis virus (TMEV) infection to generate Parkinson's disease symptoms without genetic modification or toxic injection. This approach provides a more naturalistic animal model to investigate the hypothesis that viral infection may trigger Parkinson's disease development in humans.
University of Otago research published in the Journal of Biomechanics demonstrates that smart mouthguard systems use standardized models that fail to account for biological variation across different sexes, ages, and body sizes. This limitation may result in serious traumatic brain injuries being undetected during impact assessment in rugby players.
Researchers identified distinct biological patterns in MS patients' brains that correlate with disease progression rates and severity. These patterns have a genetic component, potentially explaining why some individuals experience rapid disease advancement while others remain stable over extended periods.
Researchers identified that immune cells laden with fat droplets from damaged myelin accumulate in severe MS brain tissue and may shift from a reparative to a pro-inflammatory state. This finding offers insights into why MS progression varies between patients and could inform new therapeutic approaches.
This study used corneal confocal microscopy to detect corneal nerve loss as a potential biomarker for neurodegeneration in Parkinson's disease, multiple system atrophy, and progressive supranuclear palsy. Corneal nerve fiber density was significantly reduced in all three patient groups compared to healthy controls, with the most pronounced changes in multiple system atrophy, suggesting this imaging technique may help differentiate these neurodegenerative conditions.
