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StudiuAVC și AITÎncredere înaltă21.06.2026

Low thrombin inactivation capacity associated with increased recurrent ischemic stroke risk in young adults

This prospective cohort study of 332 young stroke survivors (median 7.6 years post-index event) identified that lower antithrombin levels, higher fibrinogen, and reduced thrombin decay (indicating lower inactivation capacity) were associated with higher recurrent ischemic event risk over 6.5 years of follow-up. The findings suggest that impaired thrombin regulation may contribute to recurrent stroke pathology in younger patients and warrant further investigation as a potential therapeutic target.

StudiuAVC și AITÎncredere bună21.06.2026

Association between Telomere Length and Neurological Disability in Stroke Patients: Analysis by Stroke Type

This prospective study of 271 stroke patients examined the relationship between telomere length (a cellular aging marker) and neurological disability measured by standardized clinical scales (NIHSS and mRS). Shorter telomeres were associated with higher stroke severity scores in ischemic stroke patients, both at emergency department admission and one day later.

StudiuAVC și AITÎncredere bună21.06.2026

Electromagnetic Fields in Ischemic Stroke Rehabilitation and Monitoring: From Laboratory to Clinical Application

This review examines the use of electromagnetic field therapies (including transcranial magnetic stimulation, transcranial direct current stimulation, and pulsed electromagnetic fields) as adjunctive rehabilitation approaches for stroke patients beyond conventional thrombolytic and thrombectomy interventions. The paper discusses the physical principles, molecular mechanisms, and evidence from preclinical and clinical studies supporting EMF applications in functional recovery and stroke monitoring.

StudiuAVC și AITÎncredere înaltă21.06.2026

Systematic Review and Meta-Analysis of Antithrombotic Therapy Delivery Within 48 Hours of Ischemic Stroke

This meta-analysis of 45 audits covering 1.18 million stroke patients found that 81.1% received antithrombotic therapy within 48 hours, falling below the 85% quality benchmark established by stroke care guidelines. Treatment delivery rates were comparable between high-income and low-to-middle-income countries, with improvements noted in studies published after 2008.

StudiuAVC și AITÎncredere înaltă21.06.2026

Comparison of American and European Guideline Recommendations for Diagnostic Workup and Secondary Prevention of Ischemic Stroke and Transient Ischemic Attack

This study compares stroke diagnostic and secondary prevention recommendations between American Heart Association/American Stroke Association (AHA/ASA) and European Stroke Organization (ESO) guidelines, analyzing 63 ESO and 82 AHA/ASA recommendations across 7 key topics. While most recommendations are similar, the guidelines assign different levels of evidence quality to many recommendations, with notable discrepancies in high-level evidence classifications.