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Sănătate mintală și neurodezvoltare

Afecțiuni neurologice

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StudiuAVC și AITÎncredere înaltă22.06.2026

Individualized Interpretation of FLAIR Vessel Hyperintensity in Ischemic Stroke and Transient Ischemic Attack: A Systematic Review

This systematic review examines FLAIR vessel hyperintensity (FVH), an imaging finding reflecting critically slowed blood flow in large artery steno-occlusions, and its clinical significance for predicting prognosis, stroke severity, infarction volume, and functional outcomes in acute ischemic stroke and TIA. The authors address conflicting findings in the literature and propose key factors for individualizing clinical interpretation of this neuroimaging marker to guide clinical decision-making.

StudiuAVC și AITÎncredere înaltă22.06.2026

Cost-Effectiveness of CYP2C19 Genotype-Guided Antiplatelet Therapy for Acute Minor Ischemic Stroke and High-Risk TIA in China

A pharmacoeconomic study evaluated whether personalizing antiplatelet therapy based on CYP2C19 genetic testing (using cilostazol or ticagrelor) is cost-effective compared to standard clopidogrel plus aspirin treatment for minor stroke and high-risk transient ischemic attack in China. The analysis found genotype-guided strategies were cost-effective with incremental cost-effectiveness ratios below accepted thresholds, with robust results across sensitivity analyses.

StudiuAVC și AITÎncredere înaltă22.06.2026

Cardiac complications following cerebrovascular disease: Comparative analysis of stroke types

This study examined cardiac complications in 721 stroke patients across three cerebrovascular event types (ischemic stroke, transient ischemic attack, and hemorrhagic stroke). Results showed ECG changes were most frequent in ischemic stroke (81.7%), with myocardial alterations common across all groups, suggesting important brain-heart interactions following stroke.

StudiuAVC și AITÎncredere bună22.06.2026

Dipping Pattern and 1-Year Stroke Functional Outcome in Ischemic Stroke or Transient Ischemic Attack

This cohort study of 1,808 patients examined whether nocturnal blood pressure dipping patterns predict 1-year functional outcomes after stroke or TIA. While reverse dipping (less than 0% nocturnal systolic BP drop) was associated with worse outcomes in initial analysis, this association became non-significant after adjusting for confounding variables.

StudiuAVC și AITÎncredere înaltă21.06.2026

Accelerated Biological Aging as a Predictor of Short- and Long-term Stroke Outcomes in Ischemic Stroke and TIA Patients

This prospective study of 7,396 stroke/TIA patients from China found that accelerated biological age—calculated using three established algorithms (PhenoAge, Klemera-Doubal, HD)—is associated with increased risk of poor stroke outcomes both short- and long-term. Patients with the highest PhenoAge acceleration showed nearly double the risk of adverse events compared to those with the lowest acceleration.