Relationship between depression and sex steroid hormones in women with epilepsy
This study investigated associations between sex steroid hormones, antiseizure medications, and depression in 112 women with epilepsy compared to 50 healthy controls, finding a 18.8% depression prevalence and significant hormonal differences including elevated testosterone and altered FSH, estradiol, progesterone, and prolactin levels. Sex steroid hormones emerge as potential biomarkers for depression risk in women with epilepsy, with implications for treatment and prognosis.