Informație de încredere. Sprijin real.

Ai întrebări despre autism, ADHD, anxietate sau depresie? Găsești ghiduri clare, verificate de specialiști. Acum, acces gratuit.

Spațiu publicitar disponibil — bannerul mare de susSpațiu publicitar disponibil — bannerul mare de sus

Explorează temele

Caută tot →

Sănătate mintală și neurodezvoltare

Afecțiuni neurologice

Articole și ghiduri recomandate

StudiuDepresieÎncredere înaltă27.06.2026

Evaluation and treatment of sleep disorders in adolescents with depression: a scoping review

This scoping review synthesizes evidence on assessment methods and interventions for sleep disturbances in depressed adolescents, analyzing 26 peer-reviewed studies published 2000-2024. The review examines evidence-based approaches including cognitive-behavioral therapy for insomnia (CBT-I), mindfulness interventions, melatonin use, and psychoeducation, with CBT-I demonstrating consistent efficacy in addressing the bidirectional relationship between mood and sleep disorders.

StudiuDepresieÎncredere bună26.06.2026

Patient perspectives on challenges and opportunities in discussing and managing anhedonia in major depressive disorder: a focus group study

This qualitative study explores patient experiences and perspectives on anhedonia (loss of pleasure) as a symptom of major depressive disorder, examining barriers to discussion and management strategies. The research identifies patient-identified challenges and opportunities for improving clinical communication and treatment approaches for this core depressive symptom.

StudiuDepresieÎncredere înaltă26.06.2026

Effects of Antidepressants on Insulin Resistance in Major Depressive Disorder: A Systematic Review

This systematic review evaluates how different antidepressant classes affect insulin resistance, a metabolic complication common in depression. Tricyclic antidepressants (nortriptyline, amitriptyline, imipramine) worsen insulin sensitivity, while SSRIs and SNRIs appear metabolically neutral; bupropion and agomelatine show potential metabolic benefits in diabetic patients.

StudiuDepresieÎncredere bună26.06.2026

Feasibility of diagnosing major depressive disorder with a panel of serum and urine biomarkers

This study tested a machine learning model combining 34 serum and urine biomarkers to objectively diagnose major depressive disorder in 160 patients and 120 controls. The biomarker diagnostic model achieved good internal discrimination (AUC 0.81) but showed moderate performance in internal-external validation (AUC 0.62-0.72), suggesting potential clinical utility pending further validation.

StudiuDepresieÎncredere bună26.06.2026

Distinct Trajectories of Amygdala Connectivity Patterns Characterize Remission vs. Non-Remission in Major Depressive Disorder

A longitudinal fMRI study tracked 48 patients with major depressive disorder over 8 weeks to identify neural biomarkers of treatment response, finding differential amygdala-supplementary motor area connectivity patterns between those who remitted versus those who did not respond to antidepressants. While baseline connectivity correlated with treatment outcomes and normalized with successful treatment, the findings require replication as they did not survive multiple comparisons correction.