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StudiuDepresieÎncredere bună30.06.2026

Antidepressant Use in Pregnancy: Assessing Knowledge and Practices Among GPs and Midwives

A New Zealand survey of 119 GPs and 62 midwives revealed significant variability in knowledge, attitudes, and practices regarding SSRI use during pregnancy, with midwives reporting greater discomfort (36% vs 11%) in managing perinatal depression. Clinical management recommendations varied considerably across respondents, and patient counseling and written information provision were frequently inadequate despite guidelines supporting SSRIs as first-line treatment when psychosocial interventions fail.

StudiuDepresieÎncredere bună30.06.2026

Gut Microbiome Diversity in Malaysian Patients with Major Depressive Disorder: A Cross-Sectional Study Protocol

This study protocol examines gut microbiota composition differences between Malaysian patients with major depressive disorder (in monotherapy and polypharmacy groups) and healthy controls using 16S rRNA gene sequencing. The research aims to fill knowledge gaps about how microbial metabolites influence mood and behavior in the Malaysian population.

StudiuDepresieÎncredere înaltă29.06.2026

Real-World Treatment Modalities and Healthcare Costs in Newly Diagnosed Major Depressive Disorder

This health services research study analyzed treatment patterns, healthcare utilization, and costs among commercially insured US patients with newly diagnosed major depressive disorder, comparing pharmacologic, nonpharmacologic, combination, and no treatment approaches. The study examined associations between patient/provider characteristics and treatment selection while measuring healthcare resource use and economic outcomes over a 2-year follow-up period.

PresăDepresieÎncredere bună28.06.2026

Large MRI analysis uncovers brain-region thinning tied to depression

This study uses MRI to investigate structural brain changes associated with major depressive disorder, examining cortical thinning patterns across brain regions. The research contributes to understanding the neurobiological mechanisms underlying depression, moving beyond symptom description toward identifying neural signatures of the condition.

StudiuDepresieÎncredere bună27.06.2026

Active versus Sham Transcranial Pulsed Electromagnetic Field Treatment for Major Depression: Protocol for a Double-Blinded Randomised Trial

This protocol describes a double-blinded, sham-controlled randomised trial evaluating transcranial pulsed electromagnetic field (T-PEMF) treatment delivered via a MoodHeadBand for patients with moderate to severe depression who have not responded to conventional therapies. The 8-week study measures depressive symptoms, cognitive function, and sleep quality using validated clinical instruments in 96 participants.

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