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StudiuLeziuni medulareÎncredere înaltă28.06.2026

Defining Abnormal Prostate-Specific Antigen Values for Prostate Cancer Screening in Spinal Cord Injury Patients

This study analyzed nearly 35,000 male veterans with spinal cord injury to establish age-adjusted PSA reference ranges for prostate cancer screening, accounting for factors like chronic urinary tract inflammation and hypogonadism that affect PSA levels in this population. The findings provide clinically relevant PSA threshold values specific to SCI patients, which differ from standard reference ranges used in the general population.

StudiuAVC și AITÎncredere bună28.06.2026

Prevalence of Familial Hypercholesterolemia in Stroke and Transient Ischemic Attack Populations: A Systematic Review and Meta-Analysis

This systematic review synthesizes evidence from four studies to estimate the prevalence of familial hypercholesterolemia (FH) in stroke and TIA patients, finding a pooled prevalence of 0.96% overall and 2.89% in large artery atherosclerosis strokes. The authors acknowledge significant heterogeneity between studies and conclude that while evidence suggests FH may be relevant to cerebrovascular disease beyond cardiology, more research is needed for firm quantitative conclusions.

StudiuAdicțiiÎncredere bună28.06.2026

Effects of Theta Burst Stimulation on Craving Severity and Biomarkers in Gambling Disorder Patients

This research investigates theta burst stimulation, a neuromodulation technique, as a potential treatment for gambling disorder by measuring changes in craving intensity and relevant biological markers. The study examines whether this brain stimulation approach can reduce gambling cravings and identify associated neurobiological changes in affected patients.

StudiuAdicțiiÎncredere bună28.06.2026

Personality and impulsivity traits associated with problematic online gaming and poker playing

This study examined how personality dimensions and impulsivity traits relate to problematic internet usage among 1,144 online MMORPG and poker players using validated psychological instruments. Neuroticism, negative urgency, positive urgency, and sensation seeking were significantly associated with higher addiction scores, while extraversion showed a protective effect, with similar patterns observed across both gaming groups.

StudiuAdicțiiÎncredere înaltă28.06.2026

Substance Use Disorder Risk in Adult Children of Parents with Severe Alcohol Use Disorder: A Nationwide Swedish Cohort Study

This Swedish register-based cohort study followed individuals from 1973–2018 to examine whether children of parents hospitalized for alcohol use disorder had elevated risks of various substance use disorders (alcohol, opioids, cannabis, stimulants, sedatives, hallucinogens, solvents) compared to controls. Children with severely affected parents showed significantly higher risks across all substance categories, with particularly elevated hazard ratios for other stimulants (5.33×) and volatile solvents (4.95×), suggesting both general and substance-specific genetic/environmental vulnerability pa

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