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The Therapeutic Engagement Index in Autism: A Research Framework for Understanding Intervention Responsiveness

This paper introduces the Therapeutic Engagement Index (TEI), a multidimensional framework for understanding why autistic children respond differently to comparable interventions by examining observable factors affecting therapeutic accessibility and engagement. TEI is proposed as a research construct—not a validated diagnostic tool or compliance measure—to identify modifiable conditions that enhance how children can access, tolerate, and benefit from therapeutic input within specific intervention contexts.

StudiuAutismÎncredere bună22.06.2026

Emotion- and Region-Specific Gaze Differences in Parents of Children With Autism Spectrum Disorder

A study using eyetracking compared visual attention patterns in parents of children with ASD versus parents of typically developing children while viewing emotional faces. Parents of children with ASD showed selective increased attention to the mouth region specifically when viewing threat-related emotions (anger, fear), suggesting emotion- and region-specific gaze allocation differences rather than generalized attentional changes.

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Cocoa polyphenols mitigate valproic acid-induced autism-like phenotypes in zebrafish via metabolic and proteomic mechanisms: a pilot study

This pilot study examined whether cocoa extract containing polyphenols could reverse autism-like behavioral and gastrointestinal abnormalities induced by valproic acid exposure in zebrafish. Cocoa co-treatment ameliorated hyperactivity and gut dysfunction while normalizing key metabolic and protein markers of cellular stress.

StudiuAutism + ADHDÎncredere înaltă22.06.2026

Vaccine Hesitancy and Refusal in Parents of Children with Autism Spectrum Disorder and Developmental Delays: A Cross-Sectional Study

This study examined vaccine refusal rates among 154 parents of children with ASD or other developmental delays, finding that reported vaccine refusal increased from 3.9% before diagnosis to 9.7% after diagnosis, primarily driven by the false belief that vaccines caused their child's condition. The research documents the real public health harm from vaccine-autism misinformation while providing no scientific support for any vaccine-autism connection.

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Epidemiological Study of Traumatic Brain and Spinal Injuries in Pediatric Patients: One-Year Analysis of Prevalence, Causes and Trends in Bulgaria

This retrospective study analyzed medical records of pediatric patients (under 18 years) admitted to a Bulgarian hospital emergency department over one year to determine prevalence, causes, and trends of traumatic brain and spinal cord injuries. Among 38,504 emergency department visits, 32% were children, with 0.3% hospitalized for neurosurgical conditions including TBI and SCI.