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This study examined cardiac complications in 721 stroke patients across three cerebrovascular event types (ischemic stroke, transient ischemic attack, and hemorrhagic stroke). Results showed ECG changes were most frequent in ischemic stroke (81.7%), with myocardial alterations common across all groups, suggesting important brain-heart interactions following stroke.
This cohort study of 1,808 patients examined whether nocturnal blood pressure dipping patterns predict 1-year functional outcomes after stroke or TIA. While reverse dipping (less than 0% nocturnal systolic BP drop) was associated with worse outcomes in initial analysis, this association became non-significant after adjusting for confounding variables.
This prospective study of 7,396 stroke/TIA patients from China found that accelerated biological age—calculated using three established algorithms (PhenoAge, Klemera-Doubal, HD)—is associated with increased risk of poor stroke outcomes both short- and long-term. Patients with the highest PhenoAge acceleration showed nearly double the risk of adverse events compared to those with the lowest acceleration.
This prospective study of 271 stroke patients examined the relationship between telomere length (a cellular aging marker) and neurological disability measured by standardized clinical scales (NIHSS and mRS). Shorter telomeres were associated with higher stroke severity scores in ischemic stroke patients, both at emergency department admission and one day later.
This review examines the use of electromagnetic field therapies (including transcranial magnetic stimulation, transcranial direct current stimulation, and pulsed electromagnetic fields) as adjunctive rehabilitation approaches for stroke patients beyond conventional thrombolytic and thrombectomy interventions. The paper discusses the physical principles, molecular mechanisms, and evidence from preclinical and clinical studies supporting EMF applications in functional recovery and stroke monitoring.