NeuroPsy InfoHub adună studii și articole verificate editorial despre sănătate mintală și afecțiuni neurologice — pentru pacienți, familii și specialiști.
A study of 403 epileptic children who discontinued anti-seizure medication after ≥2 years seizure-free identified that 12.7% experienced seizure relapse, with highest rates in genetic (25%) and structural (14.9%) etiologies. Key predictors of relapse included diagnosis age >2 years, defined etiology, focal seizures, and rapid medication withdrawal (<3 months).
This study identified prognostic factors for upper limb motor recovery in 190 patients with chronic cervical spinal cord injury using standardized neurological assessment (ASIA classification) and functional testing (Van Lushot Test). Linear discriminant analysis evaluated 10 potential predictors to determine functional outcome thresholds, providing clinicians with evidence-based rehabilitation potential estimates for tetraplegic patients.
This cross-sectional study of 100 acute ischemic stroke patients examined whether signal intensity in normal-appearing white matter on FLAIR MRI correlates with leukoaraiosis burden. Results showed that white matter signal intensity increased near leukoaraiosis borders and was independently associated with leukoaraiosis volume, suggesting structural abnormalities extend into apparently normal brain tissue.
This retrospective study of 970 stroke/TIA patients found that elevated sST2 levels independently predicted atrial fibrillation detection after stroke (AFDAS), with sST2 showing superior predictive value (AUC 0.815) compared to conventional risk factors. Adding sST2 to a conventional risk model significantly improved prediction accuracy for AFDAS in acute stroke patients.
This review examines the relationship between loneliness and social isolation as major risk factors for Alzheimer's disease and cognitive decline, with particular attention to sex differences. The authors discuss mechanisms linking isolation to AD pathology and propose approaches for developing prevention and treatment strategies based on understanding these associations.