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StudiuTraumatisme cranio-cerebraleÎncredere înaltă27.06.2026

The Effect of Mild Traumatic Brain Injury on the Hypothalamic-Pituitary-Ovarian Axis: A Narrative Review

This narrative review examines how mild traumatic brain injury (mTBI) affects the hypothalamic-pituitary-ovarian axis, particularly in females who experience disproportionately worse outcomes and higher rates of menstrual dysfunction post-injury. The authors synthesize evidence on sex differences, pituitary hormone regulation, and downstream reproductive health consequences to identify research gaps and clinical recommendations for female mTBI patients.

StudiuTraumatisme cranio-cerebraleÎncredere bună27.06.2026

Parental Knowledge and Attitudes Toward Pediatric Concussions in Saudi Arabia

A cross-sectional survey of 524 Saudi Arabian parents assessed their knowledge and attitudes regarding pediatric concussions, revealing moderate concussion knowledge (average 15.4/25) and positive attitudes (42.0/49) despite 63% lacking prior awareness. Sociodemographic factors including education level, income, and parental history of head injuries were examined as potential influencers of concussion management understanding and symptom recognition.

StudiuTraumatisme cranio-cerebraleÎncredere bună27.06.2026

External Validation of the UPFRONT Prognostic Model for Mild Traumatic Brain Injury Recovery at 6 Months

This multicenter study externally validated the UPFRONT-model, which predicts functional outcome after mild traumatic brain injury using factors like educational level, consciousness level, neck pain, and psychological variables. The model demonstrated acceptable discrimination ability but systematically underestimated recovery rates (predicted 46% vs observed 75%), suggesting need for calibration adjustments while confirming psychological variables as robust predictors.