NeuroPsy InfoHub adună studii și articole verificate editorial despre sănătate mintală și afecțiuni neurologice — pentru pacienți, familii și specialiști.
This study protocol examines gut microbiota composition differences between Malaysian patients with major depressive disorder (in monotherapy and polypharmacy groups) and healthy controls using 16S rRNA gene sequencing. The research aims to fill knowledge gaps about how microbial metabolites influence mood and behavior in the Malaysian population.
This health services research study analyzed treatment patterns, healthcare utilization, and costs among commercially insured US patients with newly diagnosed major depressive disorder, comparing pharmacologic, nonpharmacologic, combination, and no treatment approaches. The study examined associations between patient/provider characteristics and treatment selection while measuring healthcare resource use and economic outcomes over a 2-year follow-up period.
This study uses MRI to investigate structural brain changes associated with major depressive disorder, examining cortical thinning patterns across brain regions. The research contributes to understanding the neurobiological mechanisms underlying depression, moving beyond symptom description toward identifying neural signatures of the condition.
This protocol describes a double-blinded, sham-controlled randomised trial evaluating transcranial pulsed electromagnetic field (T-PEMF) treatment delivered via a MoodHeadBand for patients with moderate to severe depression who have not responded to conventional therapies. The 8-week study measures depressive symptoms, cognitive function, and sleep quality using validated clinical instruments in 96 participants.
This qualitative study explores patient experiences and perspectives on anhedonia (loss of pleasure) as a symptom of major depressive disorder, examining barriers to discussion and management strategies. The research identifies patient-identified challenges and opportunities for improving clinical communication and treatment approaches for this core depressive symptom.
