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StudiuAdicțiiÎncredere înaltă22.06.2026

Neural mechanisms linking treatment outcomes and recovery in substance-related and addictive disorders

This narrative review examines neural mechanisms underlying recovery from substance use disorders, gambling disorder, and internet gaming disorder, evaluating how pharmacological and psychological treatments impact brain processes through neuroimaging evidence. The analysis integrates major addiction models (dual process, reward deficiency syndrome) with advanced analytical approaches like machine learning to inform future treatment development strategies.

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Behavioral Addictions in ICD-11: An Ongoing Scientific Debate

The Journal of Behavioral Addictions published a 2022 debate featuring three main papers and eleven commentaries examining behavioral addictions in the ICD-11 classification system, with particular focus on compulsive sexual behavior disorder. Despite some disagreements on specific details, all contributors agreed on the importance of further research in this area.

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Working memory performance in disordered gambling and gaming: A systematic review

This systematic review of 17 peer-reviewed studies examines the relationship between working memory (a key executive function component) and gaming/gambling disorders, finding reduced working memory capacity consistently associated with both conditions. Results indicate gaming disorder and gambling disorder patients demonstrate decreased working memory performance compared to healthy controls, with severity correlating to cognitive impairment.

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Brain Activation in Gambling Disorder: An fMRI Study of Cue Reactivity to Slot-Machine Gambling

This fMRI study examines neural activation patterns in patients with gambling disorder (N=10) compared to healthy controls (N=20) when viewing gambling-related cues such as slot machines versus neutral images. The research applies established cue reactivity paradigms from addiction neuroscience to identify reward system activation and craving-related brain regions specific to behavioral gambling addiction.

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Spirituality and Behavioral Addictions: Narrative Review

This narrative review examines the complex relationship between spirituality and behavioral addictions including gaming disorder, gambling disorder, internet use problems, smartphone use problems, compulsive sexual behavior, and compulsive buying. The review synthesizes literature showing spirituality can function as either a protective factor supporting recovery or a potential risk factor, with implications for clinical practice and future research.