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StudiuAVC și AITÎncredere înaltă23.06.2026

Neuroplasticity after stroke: Adaptive and maladaptive mechanisms in evidence-based rehabilitation

This review examines how adaptive neuroplasticity promotes genuine motor recovery through neural reorganization, while maladaptive plasticity may reinforce compensatory patterns that limit functional restoration. Evidence supports intensive, repetitive, task-specific physiotherapy combined with emerging multimodal approaches (constraint-induced movement therapy, mirror therapy, robotic training, virtual reality, and non-invasive brain stimulation) as effective strategies to enhance stroke recovery.

StudiuAVC și AITÎncredere bună23.06.2026

Enhanced External Counterpulsation for Ischemic Stroke: Systematic Review and Meta-Analysis of Cerebral Blood Flow and Functional Outcomes

A meta-analysis of 15 studies (506 participants) evaluated enhanced external counterpulsation (EECP) as treatment for ischemic stroke, finding uncertain effects on cerebral blood flow but significant improvements in daily living activities, disability level, and neurological function. The study applies conservative statistical methods and acknowledges heterogeneity, indicating EECP may have clinical benefit despite unclear mechanisms.

StudiuAVC și AITÎncredere bună23.06.2026

Thromboembolic and Cerebrovascular Events as Initial Diagnostic Clues to Acromegaly: Case Series and Pathophysiologic Review

This case series presents three adults who experienced vascular events (pulmonary embolism and transient ischemic attack) that led to incidental diagnosis of acromegaly, an endocrine disorder associated with increased thrombotic and cerebrovascular risk. The cases underscore the importance of considering acromegaly in patients with unexplained vascular events, as early treatment can reduce long-term complications.

StudiuAVC și AITÎncredere înaltă23.06.2026

Arterial Input Function Dispersal on CT Perfusion Associated with Cerebral Small Vessel Disease in Stroke Patients

This retrospective study of 369 acute ischemic stroke/TIA patients found that prolonged arterial input function dispersal on computed tomography perfusion correlates with higher burden of cerebral small vessel disease markers including white matter hyperintensities and microbleeds. Each 1-second increase in dispersal independently predicted increased odds of severe small vessel disease, suggesting cardiac hemodynamic dysfunction contributes to microvascular pathology in stroke.

StudiuAVC și AITÎncredere înaltă22.06.2026

Diagnostic Accuracy of the ROSIER Scale for Identifying Stroke and Transient Ischemic Attack in Emergency Settings: Systematic Review and Meta-Analysis

This meta-analysis of 34 studies evaluated the ROSIER scale's ability to identify stroke and TIA cases in emergency settings, finding sensitivity of 0.89 and specificity of 0.76 at a cutoff score of ≥1. Performance varied by setting and assessor type, with higher sensitivity in pre-hospital EMS/paramedic administration and higher specificity in emergency department physician/neurologist assessments.

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