Ai întrebări despre autism, ADHD, anxietate sau depresie? Găsești ghiduri clare, verificate de specialiști. Acum, acces gratuit.
This systematic review synthesizes evidence for treating social anxiety disorder, recommending SSRIs as first-line pharmacotherapy and cognitive behavioral therapy as the primary psychological intervention. Additional effective options include monoamine oxidase inhibitors, benzodiazepines, pregabalin, and psychodynamic approaches, with psychological interventions showing better long-term tolerability.
This retrospective cohort study analyzed electronic health records from 2011-2020 to compare the risk of new-onset anxiety disorders in patients with hidradenitis suppurativa (a chronic skin condition) versus controls. Patients with HS had significantly higher incidence rates of anxiety disorders (5.74 vs 3.86 per 100 person-years), with adjusted analysis showing elevated risk even after controlling for demographic and clinical confounders.
A longitudinal study of 309 adolescents found that elevated startle reflex responses to unpredictable (but not predictable) threat at age 15 predicted the onset of generalized anxiety disorder by age 18, independent of prior anxiety history. Startle responses did not predict social anxiety disorder or depression, suggesting this biomarker is specific to GAD development risk.
This neuroimaging study compared brain cortical folding patterns in 90 panic disorder patients (30 with comorbid GAD, 60 without) and 65 healthy controls using MRI analysis. Results showed increased cortical gyrification in fear-network regions in panic disorder, with additional hypergyrification in worry-related brain areas specifically in the comorbid group, and correlations between cortical measures and suicidality/avoidance behaviors.
This fMRI study compared brain functional connectivity in 21 social anxiety disorder (SAD) patients, 17 generalized anxiety disorder (GAD) patients, and 30 healthy controls, finding that GAD involves stronger connectivity between the nucleus accumbens and thalamus compared to SAD. The nucleus accumbens-thalamus connectivity correlated with state anxiety severity in both anxiety groups, suggesting this network distinction may help differentiate between these two conditions.