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This study examined 181 children with ADHD (ages 7-18) and found that higher positive parenting behaviors and peer acceptance were independently associated with greater self-reported resilience. Older age and borderline intellectual functioning were protective factors inversely related to resilience in this population.
This retrospective study examined cognitive profiles in 105 children (ages 6-16) with ADHD using WISC-IV testing, comparing those with and without comorbid Specific Learning Disorder. Children with ADHD and comorbid SLD showed significantly lower scores in Verbal Comprehension, Perceptual Reasoning, and Working Memory compared to those with ADHD alone, with Working Memory being consistently the lowest cognitive domain across groups.
A 12-year-old girl with autism spectrum disorder, Landau-Kleffner syndrome, and intellectual disability developed galactorrhea, vision problems, and falls while taking risperidone, with laboratory findings showing elevated prolactin (40.2 ng/mL) but normal imaging excluding pituitary tumor. Switching from risperidone to olanzapine resulted in complete symptom resolution and prolactin normalization (2.2 ng/mL) within three months, highlighting the importance of monitoring prolactin levels in children on antipsychotic medication.
This meta-analysis of five randomized controlled trials involving 1,619 pediatric patients (ages 6-17) demonstrates that SPN-812 at doses of 100, 200, and 400 mg/day significantly improved ADHD symptoms compared to placebo on multiple validated rating scales. SPN-812 at 300 mg/day showed favorable safety profiles with no increased risk of serious adverse events like syncope, though higher doses were associated with increased somnolence and appetite suppression.
This retrospective cohort study analyzed 5,595 Japanese patients newly diagnosed with bipolar disorder to examine whether a prior depression diagnosis and its duration affected psychiatric and all-cause hospitalization rates and mortality. Patients with prior depression history showed slightly lower all-cause hospitalization risk (HR=0.87), with duration of preceding depression (≥1 year vs <1 year) not significantly altering psychiatric hospitalization outcomes.