NeuroPsy InfoHub adună studii și articole verificate editorial despre sănătate mintală și afecțiuni neurologice — pentru pacienți, familii și specialiști.
This study examined urodynamic voiding patterns in 97 MS patients with lower urinary tract symptoms, identifying sphincter dysfunction in 70% and detrusor underactivity in 23%. The research compared performance of six different diagnostic indices for assessing bladder contractility and obstruction, finding variable agreement between these parameters in this MS cohort.
A metabolomic study compared fecal metabolite profiles from 37 MS patients and 30 healthy controls using advanced mass spectrometry and multivariate statistical analysis to identify differential metabolites and their associated metabolic pathways. The research aims to reveal metabolic abnormalities associated with MS and provide insights into disease pathogenesis and potential therapeutic targets.
BTK (Bruton's tyrosine kinase) inhibitors represent a promising therapeutic approach in MS by targeting B-cell activation and immune dysregulation. This review examines the immunobiological mechanisms underlying BTK inhibition and its translation into clinical treatment strategies for multiple sclerosis patients.
This is a scientific commentary on research investigating iron accumulation patterns in the corpus callosum of patients with relapsing-remitting MS using quantitative magnetic resonance imaging. The study explores potential neuroimaging biomarkers that may contribute to understanding MS pathophysiology and disease progression.
This study examined resting-state EEG connectivity patterns in 35 relapsing-remitting MS patients versus healthy controls, finding significant disruptions in alpha and beta band coherence and phase lag that correlated with cognitive impairment on the Paced Auditory Serial Addition Test. The findings suggest EEG-derived connectivity measures may serve as objective neurophysiological biomarkers for monitoring cognitive dysfunction in MS.