Impact of Microvascular Complications on Dementia Risk in Diabetes Patients: A Systematic Review
This systematic review of five studies involving over 1.6 million participants examines how microvascular complications from diabetes—particularly neuropathy and nephropathy—increase dementia risk, with hazard ratios ranging from 1.12-1.26. Poor glycemic control (HbA1c) and its variability independently contribute to cognitive decline, with each 1% increase in HbA1c associated with an 8% increased dementia risk.


