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Anti-LGI1 Antibody-Positive Autoimmune Encephalitis Presenting with Electrographic Seizures: A Clinical Case Report

A 59-year-old woman with behavioral changes, memory impairment, and hyponatremia was diagnosed with LGI1 antibody-positive autoimmune encephalitis after brain MRI revealed temporal lobe involvement and EEG showed electrographic seizure patterns. Treatment with steroid pulse therapy, plasma exchange, and lacosamide resulted in lesion resolution within 90 days, highlighting the importance of EEG monitoring for early detection of autoimmune encephalitis.

StudiuEpilepsieÎncredere înaltă19.06.2026

Yield of Hyperventilation and Other Activation Procedures in Facilitating Epileptiform Discharges During EEG

This study compared EEG recordings with and without hyperventilation to assess their role in detecting epileptiform abnormalities across 659 patients. Hyperventilation, longer recording duration, and sleep deprivation all increased the likelihood of detecting epileptiform discharges, with hyperventilation showing particular benefit in children but not adults.

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A causal attention network with time-frequency channel feature fusion for epileptic seizure prediction

This study proposes a causal attention network (CANet) that combines dilated causal convolution and attention mechanisms to predict seizures during extended preictal periods (up to 2 hours before onset). Testing on standard epilepsy datasets showed high sensitivity (92-100%) and low false alarm rates, with average prediction times exceeding 90 minutes, potentially allowing sufficient time for therapeutic intervention.

StudiuEpilepsieÎncredere bună19.06.2026

Eslicarbazepine Use During Breastfeeding: A Case Report of Two Infants

A case report documents successful breastfeeding by a mother with drug-resistant epilepsy treated with eslicarbazepine acetate, with measured infant serum drug levels at 9.1% and 7.5% of maternal concentration and no adverse effects at 13 months follow-up. The authors conclude that breastfeeding may be considered under clinical supervision for healthy term infants of mothers on eslicarbazepine monotherapy, while noting that safety data remain limited.

StudiuEpilepsieÎncredere bună19.06.2026

Serum subfatin levels as a potential biomarker for epileptic seizure diagnosis: A case-control study

This case-control study of 132 epilepsy patients and 131 controls found significantly lower serum subfatin levels in epilepsy patients compared to controls, with ROC analysis showing good diagnostic discriminatory power (AUC 0.84). The authors propose subfatin as a promising biomarker that may reflect neuroinflammatory processes in epileptogenesis, with potential diagnostic and prognostic utility.