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StudiuADHDÎncredere înaltă30.06.2026

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StudiuAutism + ADHDÎncredere înaltă26.06.2026

Agomelatine versus escitalopram for depression in people with epilepsy: A randomized controlled trial

This double-blind randomized trial compared agomelatine and escitalopram in 51 people with epilepsy and major depressive disorder, evaluating effects on depression, seizure frequency, sleep, cognition, and quality of life. Both medications improved depression similarly with minimal adverse events; escitalopram showed greater quality-of-life improvement while agomelatine showed better verbal memory outcomes, with no significant effects on seizure frequency in either group.

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Effect of Prior Depression Diagnosis on Bipolar Disorder Outcomes: A Retrospective Cohort Study

This retrospective cohort study analyzed 5,595 Japanese patients newly diagnosed with bipolar disorder to examine whether a prior depression diagnosis and its duration affected psychiatric and all-cause hospitalization rates and mortality. Patients with prior depression history showed slightly lower all-cause hospitalization risk (HR=0.87), with duration of preceding depression (≥1 year vs <1 year) not significantly altering psychiatric hospitalization outcomes.

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Ancient Brainstem Neurons Discovered to Control Attention

Researchers identified an evolutionarily conserved circuit of inhibitory neurons in the brainstem that regulates selective spatial attention. This discovery may enhance understanding of attention mechanisms relevant to conditions like ADHD.