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University of Otago research published in the Journal of Biomechanics demonstrates that smart mouthguard systems use standardized models that fail to account for biological variation across different sexes, ages, and body sizes. This limitation may result in serious traumatic brain injuries being undetected during impact assessment in rugby players.
Researchers identified distinct biological patterns in MS patients' brains that correlate with disease progression rates and severity. These patterns have a genetic component, potentially explaining why some individuals experience rapid disease advancement while others remain stable over extended periods.
This study used corneal confocal microscopy to detect corneal nerve loss as a potential biomarker for neurodegeneration in Parkinson's disease, multiple system atrophy, and progressive supranuclear palsy. Corneal nerve fiber density was significantly reduced in all three patient groups compared to healthy controls, with the most pronounced changes in multiple system atrophy, suggesting this imaging technique may help differentiate these neurodegenerative conditions.
Rhythmic auditory stimulation (RAS) demonstrates effectiveness in improving gait, balance, and fall prevention in Parkinson's disease through mechanisms involving neural entrainment and oscillatory brain coupling. Research suggests RAS-based interventions may address additional PD symptoms and extend to atypical parkinsonian disorders, though further study is warranted.
This study identified prognostic factors for upper limb motor recovery in 190 patients with chronic cervical spinal cord injury using standardized neurological assessment (ASIA classification) and functional testing (Van Lushot Test). Linear discriminant analysis evaluated 10 potential predictors to determine functional outcome thresholds, providing clinicians with evidence-based rehabilitation potential estimates for tetraplegic patients.
