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Pseudotumoral MS (PTMS) presents as large lesions (>2 cm) that mimic brain tumors on imaging but represent an aggressive MS variant. This retrospective study of 18 patients (83% female) with relapsing-remitting MS found delayed diagnosis in some cases, predominantly motor symptoms, and favorable long-term clinical improvement with standard MS treatment.
This case-control study investigates the relationship between testosterone levels and relapsing-remitting multiple sclerosis (RRMS), examining whether hormonal factors influence disease progression. The research uses a comparative methodology to evaluate testosterone's potential role in MS pathophysiology among affected and unaffected populations.
This study examines MS patients' understanding of how multiple sclerosis affects pregnancy, childbirth, and postpartum outcomes. It addresses an important clinical gap by assessing patient knowledge on reproductive health management with MS.
This cross-sectional study of 80 Parkinson's patients examined relationships between objectively measured daily physical activity (step count) and symptom severity using wearable devices over 6 weeks. Higher daily activity was associated with significantly reduced bradykinesia and paradoxically increased mild dyskinesia, supporting the role of physical activity in managing Parkinson's motor symptoms.
This study investigates the relationship between gray matter volume loss in Parkinson's disease psychosis (PDP) and brain expression of cannabinoid receptor genes, finding a significant association with CB1 but not CB2 receptor expression. The findings suggest the endocannabinoid system may play a role in PDP pathophysiology.
