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This research investigates theta burst stimulation, a neuromodulation technique, as a potential treatment for gambling disorder by measuring changes in craving intensity and relevant biological markers. The study examines whether this brain stimulation approach can reduce gambling cravings and identify associated neurobiological changes in affected patients.
This study examined how personality dimensions and impulsivity traits relate to problematic internet usage among 1,144 online MMORPG and poker players using validated psychological instruments. Neuroticism, negative urgency, positive urgency, and sensation seeking were significantly associated with higher addiction scores, while extraversion showed a protective effect, with similar patterns observed across both gaming groups.
This Swedish register-based cohort study followed individuals from 1973–2018 to examine whether children of parents hospitalized for alcohol use disorder had elevated risks of various substance use disorders (alcohol, opioids, cannabis, stimulants, sedatives, hallucinogens, solvents) compared to controls. Children with severely affected parents showed significantly higher risks across all substance categories, with particularly elevated hazard ratios for other stimulants (5.33×) and volatile solvents (4.95×), suggesting both general and substance-specific genetic/environmental vulnerability pa
This randomized controlled trial evaluated long-term effects of STAND (cognitive-behavioral therapy combined with motivational interviewing) versus usual care for adolescents with ADHD across community clinics over 3 years. Licensed therapists delivering STAND showed superior outcomes in hyperactivity/impulsivity, parent-teen conflict, and organizational/time management skills compared to unlicensed providers, though intent-to-treat analyses showed no overall group differences.
Researchers developed a mannose-modified nanomicelle (Man-LA) designed to deliver hydrogen sulfide directly to the brain via GLUT1 transporters in astrocytes, and demonstrated in rat autism models that it alleviates behavioral symptoms while promoting aerobic glycolysis and protecting hippocampal neurons. The study identifies dysregulation of astrocytic aerobic glycolysis and H₂S signaling as potentially important in autism pathophysiology, though these findings remain preclinical and require human validation.
