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StudiuTraumatisme cranio-cerebraleÎncredere înaltă28.06.2026

Neuropsychological Assessment in Mild Traumatic Brain Injury: Diagnostic Frameworks and Methodological Considerations

This article critically examines divergent diagnostic criteria for mild traumatic brain injury (mTBI) used across clinical and forensic settings, including ACRM, VA/DoD, DSM-5-TR, ICD-11, and CISG frameworks, highlighting their differing evidentiary standards and practical limitations. The authors review evidence-based approaches to diagnostic uncertainty, emerging blood biomarkers (GFAP, UCH-L1, NfL, S100B), and the scope of neuropsychological opinion in legal contexts, addressing challenges in retrospective determination and mechanistic complexity in injury mechanisms.

StudiuScleroză multiplăÎncredere înaltă28.06.2026

Fear of Relapse in Multiple Sclerosis: The Roles of Perfectionism and Intolerance of Uncertainty

This cross-sectional study of 222 RRMS patients examined how perfectionism and intolerance of uncertainty contribute to fear of relapse using validated psychological scales. Results showed perfectionism significantly predicts fear of relapse both directly and indirectly through intolerance of uncertainty, which mediates approximately 48% of this relationship.

StudiuEpilepsieÎncredere înaltă28.06.2026

Associations between epileptic seizures in pregnancy and adverse pregnancy outcomes: A systematic review and meta-analysis

This meta-analysis of 25 observational studies (24,596 pregnancies) found that pregnant women with epilepsy who experience seizures have increased risks of caesarean delivery, peripartum depression, preterm birth, and small-for-gestational-age infants compared to those without seizures. The review also examined how socioeconomic factors may influence seizure control during pregnancy.

StudiuLeziuni medulareÎncredere înaltă28.06.2026

Defining Abnormal Prostate-Specific Antigen Values for Prostate Cancer Screening in Spinal Cord Injury Patients

This study analyzed nearly 35,000 male veterans with spinal cord injury to establish age-adjusted PSA reference ranges for prostate cancer screening, accounting for factors like chronic urinary tract inflammation and hypogonadism that affect PSA levels in this population. The findings provide clinically relevant PSA threshold values specific to SCI patients, which differ from standard reference ranges used in the general population.

StudiuAVC și AITÎncredere bună28.06.2026

Prevalence of Familial Hypercholesterolemia in Stroke and Transient Ischemic Attack Populations: A Systematic Review and Meta-Analysis

This systematic review synthesizes evidence from four studies to estimate the prevalence of familial hypercholesterolemia (FH) in stroke and TIA patients, finding a pooled prevalence of 0.96% overall and 2.89% in large artery atherosclerosis strokes. The authors acknowledge significant heterogeneity between studies and conclude that while evidence suggests FH may be relevant to cerebrovascular disease beyond cardiology, more research is needed for firm quantitative conclusions.

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