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An FDA-approved rheumatoid arthritis drug that blocks IL-6 receptors significantly reduced excessive alcohol consumption in alcohol-dependent female mice by suppressing neuroinflammation in the central amygdala. This mechanism aligns with elevated IL-6 expression observed in postmortem brain tissue from individuals with alcohol use disorder, suggesting a potential therapeutic target.
This neuroimaging study compared brain structural connectivity in 25 individuals with gambling disorder versus 28 healthy controls using diffusion tensor imaging and probabilistic tractography. The gambling disorder group showed increased striatal connectivity but reduced frontal lobe connectivity and fewer neural hubs, suggesting impaired network integration related to risk-taking control.
This research investigates theta burst stimulation, a neuromodulation technique, as a potential treatment for gambling disorder by measuring changes in craving intensity and relevant biological markers. The study examines whether this brain stimulation approach can reduce gambling cravings and identify associated neurobiological changes in affected patients.
This study examined how personality dimensions and impulsivity traits relate to problematic internet usage among 1,144 online MMORPG and poker players using validated psychological instruments. Neuroticism, negative urgency, positive urgency, and sensation seeking were significantly associated with higher addiction scores, while extraversion showed a protective effect, with similar patterns observed across both gaming groups.
This work examines the intersection of gambling disorder and legal accountability within the Brazilian justice system, analyzing how behavioral addiction affects criminal responsibility determinations. It addresses forensic and legal implications of recognizing gambling disorder as a behavioral addiction in criminal proceedings.
