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StudiuLeziuni medulareÎncredere bună30.06.2026

Predictors of upper limb function in patients with cervical tetraplegia

This study identified prognostic factors for upper limb motor recovery in 190 patients with chronic cervical spinal cord injury using standardized neurological assessment (ASIA classification) and functional testing (Van Lushot Test). Linear discriminant analysis evaluated 10 potential predictors to determine functional outcome thresholds, providing clinicians with evidence-based rehabilitation potential estimates for tetraplegic patients.

StudiuAVC și AITÎncredere înaltă30.06.2026

Subtle white matter intensity changes on FLAIR imaging in patients with ischemic stroke

This cross-sectional study of 100 acute ischemic stroke patients examined whether signal intensity in normal-appearing white matter on FLAIR MRI correlates with leukoaraiosis burden. Results showed that white matter signal intensity increased near leukoaraiosis borders and was independently associated with leukoaraiosis volume, suggesting structural abnormalities extend into apparently normal brain tissue.

StudiuAVC și AITÎncredere bună30.06.2026

Soluble Suppression of Tumorigenicity 2 as a Biomarker for Atrial Fibrillation Detected After Stroke: A Retrospective Clinical Study

This retrospective study of 970 stroke/TIA patients found that elevated sST2 levels independently predicted atrial fibrillation detection after stroke (AFDAS), with sST2 showing superior predictive value (AUC 0.815) compared to conventional risk factors. Adding sST2 to a conventional risk model significantly improved prediction accuracy for AFDAS in acute stroke patients.

StudiuDemențeÎncredere înaltă30.06.2026

The impact of loneliness and social isolation on cognitive decline and Alzheimer's disease development

This review examines the relationship between loneliness and social isolation as major risk factors for Alzheimer's disease and cognitive decline, with particular attention to sex differences. The authors discuss mechanisms linking isolation to AD pathology and propose approaches for developing prevention and treatment strategies based on understanding these associations.

StudiuAdicțiiÎncredere bună30.06.2026

Neural fingerprints of gambling disorder using diffusion tensor imaging

This neuroimaging study compared brain structural connectivity in 25 individuals with gambling disorder versus 28 healthy controls using diffusion tensor imaging and probabilistic tractography. The gambling disorder group showed increased striatal connectivity but reduced frontal lobe connectivity and fewer neural hubs, suggesting impaired network integration related to risk-taking control.

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